둥굴레 추출물 및 분획의 과산화지질 생성 저해효과

• 영문명: Anti-lipid Peroxidative Effect of Extracts and its Fractions
• 발행기관: 대한약학회
• 저자명: 김주향(Ju Hyang Kim) 양기숙(Ki Sook Yang)
• 간행물 정보: 『약학회지』제46권 제4호 (2002년), 242~246쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2002.08.31

영문 초록

The rhizoma of Polyonatum odoratum(Liliaceae) promotes the production of body fluid and relives dryness symptoms and has hypoglycemic effect. In order to evaluate the prevention of lipid peroxidative efficacy of P.odoratum, its extracts (Et2O and MeOH ex.) and its fractions (H2O, 20% MeOH,40% MeOH, 60% MeOH and 100% MeOH fr.) were measured by TBARS assay on rat liver 59 and human erythrofrte ghost membrane. The order of anti-lipid peroxidative effect was as follows : Et2O ex. >40% MeOH fr. >60% MeOH fr. >100% MeOH fr. Based on these results, we conclude that mombrane lipid peroxidation is inhibited iu yifrp by addition of P.odoratum Ether extract and its gradient MeOH fractions excepts H2O fr, and which have significant hepatoprotective activity in CC14-treated rats.

키워드

Polygonatum odoratum anti-lipid peroxidative TBARS assay.