고마리 지상부의 항산화활성 성분

• 영문명: Antioxidative Components from the Aerial Ptrts Persicaria thunbergii
• 발행기관: 대한약학회
• 저자명: 이기택(Ki Taek Lee) 구충환(Chung Hwan Ku) 은재순(Jae Soon Eun) 신태용(Tae Yong Shin) 임종필(Jong Pil Lim) 엄동욱(Dong Ok Eorn) 지옥표(Ok Pyo Zee) 김대근(Dae Keun Kim)
• 간행물 정보: 『약학회지』제45권 제6호 (2001년), 611~616쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2001.12.31

영문 초록

The antioxidant activity of.Persicaria thunbergii(Polygonaceae) was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. The methanol extract of P. thunbergii showed strong radical scavenging activity at an IC50 concentration of 12.2mcg/ml, and thus fractionated by solvent extraction. The EtOAc soluble fraction was stronger than the others, and was further purified by silica gel and Sephadex LH-20 column chromatography. Antioxidant isorhamnetin (1), quercetin (2), quercitrin (3) and isoquercitrin (4) were isolated from the EtOAc soluble fraction. And isorhamnetin-3-sulfate (5) was isolated from the n-BuOH fraction. Compounds 2,3 and 4 were found to have strong antioxidative potency.

키워드

Persicaria thunbergii polygonaceae anitoxidant activity.