구절호에서 분리한 linarin의 생리활성

• 영문명: Biological Activities of Linarin from Chrysanthemum zawadskii var. latilobum
• 발행기관: 대한약학회
• 저자명: 김영윤(Young Yoon Kim) 이숙연(Sook Yeon Lee) 임동술(Dong Sool Yim)
• 간행물 정보: 『약학회지』제45권 제6호 (2001년), 604~610쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2001.12.31

영문 초록

Chrysanthemum zawadskii var. latilobum (Compositae), which is called Gu-lul- Cho, has been used as traditional medicine in pneumonia, bronchitis, common cold, pharyngitis, bladder-related disorders, women's diseases, and hypertension, etc. In this study, we have investigated various biological activities of methanol extracts and their main component, linarin isolated from this herb. The antipyretic erect of them was tested by Brewers yeast method and the antiinf1ammatory activities, with arachidonic acid, o-tet-radecanoylphorbol 13-acetate and carrageenan. Their antipretic and antiinflammatory activities were more potent than acetaminophene and aspirin. They also showed stronger hepatoprotective activities than ones of silymarin in mice.

키워드

Chrysanthemum zawadskii var. latilobum linarin antipyretic antiinflammatory hepatoprotective activities.