상기생의 트라이테르펜 및 페놀성 성분

• 영문명: Triterpenes and Phenolic Constituents from Viscum album L.
• 발행기관: 대한약학회
• 저자명: 최상진(Sang Zin Choi) 권학철(Hak Cheol Kwon) 정애경(Ae Kyung Chung) 최상운(Sang Un Choi) 김경란(Kyung Ran Kim) 이선미(Sun Mee Lee) 표석능(Suhk Neung Pyo) 이강노(Kang Ro Lee)
• 간행물 정보: 『약학회지』제45권 제6호 (2001년), 591~598쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2001.12.31

영문 초록

The phytochemical study of Viscum album (Loranthaceae) led to the isolation of twelve compounds, lupeol (1), betulonic acid (2), betulinic acid (3), termitic acid (4), ursolic acid (5), β-sitosterol (6),α- spinasterol (7), oleanolic acid (8), 5- hydroxy-1-(4'- hydoxyphenyl)-7-(4"-hydroxyphenyl)-hepta-1-en-3-on (9), 2'- hydroxy- 4',6'-dimethoxychalcone-4-0-glucoside (10), 2'-hydroxy-4',6'-dime thoxychalcon e-4-0-[apio-syl(1-> 2)]glucoside (11) and sringin (12). Their structures were established by chemical and spectroscopic methods. The cytotoxicity of the isolated compounds was evaluated by sulforhodamine B assay against five cultured human tumor cell lines.

키워드

Viscum album Loranthaceae lupeol betulonic acid betulinic acid terminic acid ursolic acid beta-sitosterol a-spinasterol oleanolic acid 5-hydroxy-1-(4'-hydoxyphenyl)-7-(4"-hydroxyphenyl)-heptal-en-3-on 2'-hydroxy-4',6'-dim ethoxychalcone-4-0-glucoside 2'-hydroxy-4',6'-dim ethoxychalcone-4-0-[apiosy1(1→2)]glucoside syringin cytotoxicity.