대극과식물 등대풀로부터 분리한 가수분해형 탄닌의 tyrosinase활성억제효과

• 영문명: Inhibitory Effect of Hydrolysable Tannins Isolated from the Euphorbia helioscopia on Mushroom Yrosinase Activitiy in vitro
• 발행기관: 대한약학회
• 저자명: 김진준(Jin Joon Kim) 이주상(Joo Sang Lee) 김소영(So Young Kim) 김정아(Jeong Ah Kim) 정시련(See Ryun Jung) 장태수(Tae Soo Jang) 이승호(Seung Ho Lee)
• 간행물 정보: 『약학회지』제45권 제2호 (2001년), 214~219쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2001.04.30

영문 초록

Nineteen hydrolyable tannins isolated from Euphorbia helioscopia(Euphorbiaceae) were tested for the inhibitory effect on mushroom tyrosinase activity in vitro. Inhibitory effect of gallotannin group exhibited more potent than that of phenocarboxylic acid and ellagitannin groups against the enzyme activity. The inhibitory activity by pentagalloyl glucose on mushroom tyrosinase was more potent(IC50, 4.9uM) than that of kojic acid(IC50, 8.7uM)

키워드

Euphorbia helioscopia hydrolysable tannins mushroom tyrosinase activity pentagalloyl glucose.