Formamidine 종의 합성 및 살균성

• 영문명: Studies on the Synthesis and Bactericidal Activity of Formamidines
• 발행기관: 대한약학회
• 저자명: 이계주(Gye Joo Rhee) 장반섭(Pan Sub Chang)
• 간행물 정보: 『약학회지』제17권 제1호 (1973년), 17~20쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1973.03.31

영문 초록

Six novel compounds of N,N-dimethyl-N''-(6-substituted-2-benzothiazolyl) formamidines and six novel compounds of N,N-dimethyl-N''-(substituted-phenyl)formamidines were synthesized. They were evaluated for their bactericidal activities against Salmonella typhosa, Escherichia coli, Vibrio cholera, Staphylococcus aureus, Sarcina lutea and for their fungicidal activities against Saccharomyces cereviseae, Candida albicans. It was found that these compounds were considerably more active than phenol, especially against Vibrio cholera, and N,N-dimethyl-N''-(4-methyl-phenyl)formamidine, N,N-dimethyl-N''-(2-methyl-4-bromo-phenyl)formanidine showed most potent bactericidal activities.