Cathepsin B 저해물질을 생산하는 Streptomyces aburabiensis의 분리 및 동정

• 영문명: Isolation and Identification of Streptomyces aburabiensis Producing Cathepsin B Inhibitor
• 발행기관: 대한약학회
• 저자명: 박상진(Sang Jin Park) 이현숙(Hyun Sook Lee) 김인섭(In Seop Kim) 김형태(Hyoung Tae Kim) 윤성준 이계준
• 간행물 정보: 『약학회지』제39권 제3호 (1995년), 297~305쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1995.06.30

영문 초록

The aim of the present study was to develop strains of actinomycetes producing low molecular weight cathepsin B inhibitor. Among 700 isolates from soil samples, a strain of Streptomyces sp. SMF30 producing cathepsin B inhibitor showing specificity and heat stability was selected by an economical and effective screening method. 50 units characteristics for major cluster analysis and 34 units characteristics for minor cluster were tested and the data were analyzed numerically using the TAXON program. The isolate SMF30 was identified as a strain of Streptomyces aburabiensis.