키틴과 파추출액 반응물의 항암 작용

• 영문명: Antitumor Activity of Reaction Mixture of Chitin and Green Onion Extract
• 발행기관: 대한약학회
• 저자명: 김영식(Yeong Sik Kim) 박경신(Kyung Shin Park) 장일무(Il Moo Chang) 현진원(Jin Won Hyun) 박재갑(Jae Gahb Park) 박호군(Ho Koon Park)
• 간행물 정보: 『약학회지』제38권 제5호 (1994년), 579~585쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1994.10.30

영문 초록

Antitumor activity was tested by administration of reaction mixture of green onion extract and chitin to mice bearing sarcoma-180 cells. An intraperitoneal injection of mixture(20mg/kg/day) to mice gave an 52% inhibition of tumor growth. Inhibition of tumor growth was found to be dose-dependent. When eighty miligrams of the mixture were administered, the weight of tumor was reduced significantly. HPLC analysis indicated the mixture was composed of N-acetyl-D-glucosamine, N-acetylchitobiose and N-acetylchitotriose.