프로토베르베린 관련 화합물합성 및 항균작용

• 영문명: Synthesis of Protoberberine Related Compounds and Their Antifungal Activities
• 발행기관: 대한약학회
• 저자명: 김신규(Sin Kyu Kim) 김동현(Dong Hyun Kim) 정경희(Kyung Hee Chung) 황순호(Soon Ho Hwang) 김재현(Jae Hyun Kim)
• 간행물 정보: 『약학회지』제38권 제1호 (1994년), 91~96쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1994.02.28

영문 초록

Irradiation of the berberinephenolbetaine [1] effected valence tautamerization to give 8,14-cycloberbine[2], which was converted to the spirobenzylisoquinolines by regioselective C-N bond cleavage A variety of ring systems such as compounds [4], [5] and [6] were indroduced by the structural modification of berberinephenolbetaine.

키워드

m-chloroperbenzoic acid berberinephenolbetaine benzoyl chloride 8,14-cycloberbine bis(2-chloroethyl)amine 2-methylaziridine N-C bond cleavage dimethyl acetylenedicarboxylate diethyl acetylenedicarboxylate.