Methyl-6-deoxy-beta-L-idopyranoside의 합성

• 영문명: Stereospecific Synthesis of Methyl-6-deoxy-beta-L-idopyranoside
• 발행기관: 대한약학회
• 저자명: 민신홍(Shin Hong Min) 박복구(Bok Ku Park) 옥광대(Kwang Dae Ok)
• 간행물 정보: 『약학회지』제30권 제6호 (1986년), 352~355쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1986.12.30

영문 초록

Methyl-6-deoxy-beta-L-idopyranoside was prepared in good yield by treatment of methyl 2,3,4-tri-O-benzyl-6-deoxy-alpha-D-xylo-hex-5-enopyranoside with H2 on pd, followed by reaction of Na/NH3 at -50oC. The ratio of L-idopyranoside and D-glucopyranoside was 7 to 1 in 80.7%. It was confirmed that L-idopyranoside was 1C conformation as being expected.