Micellar Solubilization of Cholesterol, Cholesteryl Myristate and Gallstones by Synthetic Surfactants

• 발행기관: 대한약학회
• 저자명: Suk Kyu Han Nam Hong Kim
• 간행물 정보: 『약학회지』제21권 제3호 (1977년), 135~140쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1977.09.30

영문 초록

Solubilization of cholesterol, its fatty acid esters and gallstones were undertaken employing nonionic, anionic and cationic surfactants. Cholesterol was effectively solubilized by all of these surfactants. Cationic surfactants were most effective. However, cholesteryl myristate was not solubilized at all. In the dissolution test of gallstones in surfactant solutions, cationic surfactant solutions were exceptionally effective in dissolving gallstones. These results suggest the possible existence of interaction between alkylammonium radical and cholesterol on micellar surface.