경도인지장애에서 우울증 유병률과 관련요인

• 영문명: Prevalence and Associated Factors of Depression in Mild Cognitive Impairment
• 발행기관: 대한노인정신의학회
• 저자명: 이준호(Jun Ho Lee) 최영민(Young Min Choe) 변민수(Min Soo Byun) 최효정(Hyo Jung Choi) 백혜원(Hyewon Baek) 손보경(Bo Kyung Sohn) 이동영(Dong Young Lee)
• 간행물 정보: 『노인정신의학』노인정신의학 제18권 제2호, 86~91쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2014.10.31

영문 초록

Objective：The aims of this study were to investigate the prevalence of co-morbid depression and related factors of depression in mild cognitive impairment (MCI) patients. Methods：Nine hundred and six MCI individuals were included in this study. Depression was defined as major and minor depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV). Depression-related demographic and clinical factors were also explored through multivariate logistic regression analysis. Results：In MCI patients, the prevalence of depression as defined according to the DSM-IV diagnostic criteria was 1.8% for major depressive disorder, 11.4% for minor depressive disorder, and overall 13.2% for both. Multivariate logistic regression showed that increased prevalence of overall depression was associated with female gender and non-amnestic subtype of MCI. Conclusion：Our findings based on a large number of MCI subjects who visited memory clinic indicated that more than ten percent of MCI patients have comorbid depression. In addition, female and non-amnestic subtype of MCI patients seems to be more vulnerable to depression.

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대상 및 방법

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키워드

Mild cognitive impairment Depression Major depressive disorder Minor depressive disorder Prevalence