백량금 열매 추출물이 항산화 및 항염작용에 미치는 영향

• 영문명: Effects of Anti-oxdiant activity and Anti- inflammation action on Extracts Isolated from A. crenata fruit
• 발행기관: 한국인체미용예술학회
• 저자명: 유선희(Seon-Hee You) 윤미연(Mi-Yun Yoon)
• 간행물 정보: 『한국인체미용예술학회지』한국인체미용예술학회지 제14권 제3호, 197~208쪽, 전체 12쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2013.09.20

영문 초록

To investigate the physiological activity of A. crenata fruit extracts, both antioxidant and anti-inflammatory effects were observed. The extracts showed 3 major peaks with retention times of 2.9, 3.0 and 3.3 mins in HPLC analysis, which may be predicted as bergenin and syringic acid. The extracts did not show any cytotoxicity at the concentration of 1 ㎍/㎖ for 48 h in B16 melanoma cells, but cytotoxicity was noted at 10 ㎍/㎖ for 24 h. In a cell-free system, syringic acid showed antioxidant activity in a dose-dependent manner, whereas the extracts did not. However, the extracts showed significant antioxidant activity in a cell-cultured system. On the other hand, the extracts significantly inhibited melittin-induced arachidonic acid release and β-hexosaminidase release in RBL 2H3 cells. These results suggest that Ardisia crenata fruit extracts may be useful for development as anti-inflammatory agents.

목차

Abstract

1. 서론

2. 재료 및 방법

3. 실험결과 및 고찰

4. 결론

참고문헌

키워드

백량금 열매 항산화제 아라키돈산 헥소스 아미니다아제 A. crenata fruit Anti-oxidant Arachidonic acid β-hexosaminidase