노인성 우울증에 대한 약물치료지침

• 영문명: Guidelines for the Drug Treatment of Geriatric Depression
• 발행기관: 대한노인정신의학회
• 저자명: 이동영(Dong Young Lee)
• 간행물 정보: 『노인정신의학』노인정신의학 제7권 제1호, 23~33쪽, 전체 11쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2003.06.30

영문 초록

The author reviews general principles and guidelines regarding the drug treatment of geriatric depression. Older depressed patients are more prone to drug adverse reactions and drug-drug interactions than younger patients because of pharmacokinetic and pharmacodynamic changes resulting from age-related physiological changes, physical illnesses, polypharmacy, and various other factors. Therefore, a careful evaluation for physical illnesses and drugs needed to be made before strating antidepressant medication and "start low, go slow" dosing principle should be kept in mind. All classes of antidepressants available for younger depressed patients could be used for the geriatric patients. Choice of specific antidepressant drugs depend on potential adverse reactions and interactions of each agent, subtype or severity of depression, and comorbid diseases, such as stroke, dementia, Parkinson's disease, and heart disease. ECT must be also considered for antidepressant-resistant severe geraitric depression.

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키워드

노인 우울증 항우울제 약물치료 Geraitric depression Antidepressants Treatment