방사선 조사가 체내 아스코베이트(비타민 C)농도에 미치는 영향

• 영문명: Effect of Radiotherapy on the Ascorbate (Vitamin C) Levels in Whole Blood and Plasmas
• 발행기관: 대한방사선종양학회
• 저자명: 채규영(Gyu Young Chai) 윤희상(Hee Sang Yoon)
• 간행물 정보: 『대한방사선종양학회지』제11권 제2호, 227~231쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1993.12.29

영문 초록

The role of ascorbate as an antioxidant in the prevention and cure of disease that result from free radicals has been of considerable interest and controversy lately. As an antioxidant, we can expect it to protect against radiation damage caused by free radicals that are produced when radiation, especially sparsely ionizing radiation, interacts with living tissues. The plasma and whole blood concentration of ascorbate was analyzed before and just after the radiation therapy for the purpose of estimating the consumption amount of ascorbate during radiotherapy. Whole blood ascorbate was decreased from 1.82 mg/dl to 1.58 mg/dl, plasma ascorbate was decreased from 1.13 mg/dl to 1.08 mg/dl, and urine ascorbate was decreased from 9.33 mg/dl to 6.96 mg/dl after radiotherapy. Although the difference was not significant statistically, further human study should be followed to define the role of ascorbate as a radioprotector.

키워드

Ascorbate Radioprotector Radiotherapy