수술 불가능한 췌장암 환자에서 방사선 치료의 역할

• 영문명: Role of Radiotherapy in Unresectable Pancreatic Carcinoma
• 발행기관: 대한방사선종양학회
• 저자명: 신현수(Hyun Soo Shin) 성진실(Jinsil Seong) 오원용(Won Yong Oh) 김귀언(Gwi Eon Kim)
• 간행물 정보: 『대한방사선종양학회지』제11권 제1호, 119~126쪽, 전체 8쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1993.06.30

영문 초록

From 1988 to 1991, nineteen patients with unresectable localized pancreatic carcinoma were treated with radiotherapy and/or hyperthemia or in combination with chemotherapy. Radiation dose of 4500-5000 cGy with or without additional 500-1000 cGy was administered over 5 to 6 weeks to the pancreatic tumor area using 10 MV linear accelerator. Five of 19 patients were given chemotherapy, either neoadjubant or maintenance setting with FAM regimen (5-FU, adriamycin and mitomycin C), which was repeated every 4 weeks for one wear or until progression. Symptomatic palliation was achieved in 17 among 19 patients (89%) and objetive response (complete or partial response in CT finding) was achieved in 5 among 11 patients (45%). The median survival time was 9 months and one-year survival rate, 32%. Local- regional failure was documented in 10 among 13 patients (77%) and distant failures were found in the liver (3 patients) and carcinomatosis (2 patients). Prognostic significance of various factors such as age, sex, performance status, tumor location, stage, etc. were assessed. Any factors did not have the prognostic significance in univariate analysis. Treatment was well tolerated in most of the patients with only mild to moderate toxicity.

목차

abstract

서론

대상 및 방법

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고찰

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참고문헌

키워드

Pancreatic carcinoma Unresectable Radiotherapy.