전신성 홍반성 루프스에 동반된 기저핵 경색 1례

• 영문명: A Case of Basal Ganglia Infarct Associated with SLE.
• 발행기관: 대한소아신경학회
• 저자명: 정희영(Hee-Young Cheong) 윤희철(Hee-Chul Yoon) 서은숙(Eun-Sook Suh)
• 간행물 정보: 『Annals of Child Neurology(구 대한소아신경학회지)』대한소아신경학회지 제12권 제2호, 229~234쪽, 전체 6쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2004.11.30

국문 초록

저자들은 생후 19개월 환아에서 우측 편마비로 내원하여 뇌기저핵 경색이 있었던 환아에서 전신성홍반성 루프스와 관련됨을 발견하여 문헌 고찰과 함께 보고하는 바이다.

영문 초록

Systemic lupus erythematosus(SLE), a rheumatic disease of unknown causes, is characterized by autoantibodies directed against self-antigens, resulting in inflammatory damages to target organs including kidney, blood-forming cells, and central nervous system. The prevalence rates are higher in Native Americans, Asians, Latin Americans and black people. A female to male ratio of approximately 2 : 1 occurs before puberty, and 4 : 1 after puberty. Children of SLE most frequently present with fever, fatigue, arthralgia or arthritis, and rashes. The diagnosis is confirmed by clinical and also laboratory manifestations satisfying at least 4 out of 11 criteria. A central nervous system is not rarely involved in children of SLE with the prevalence rate of 23-44%. However, cerebral infarcts are not a common phenomenon and can be seen only for 6% of children with SLE. There have been no cases reported in Korea. This is why we present a case of basal ganglia infarct associated with SLE in a 19-month old girl. We report this case with a brief review of related literature.

키워드

Systemic lupus erythematosus Basal ganglia infarct Cerebrovascular disease