조화운동불능을 동반하지 않은 Miller Fisher 증후군 2례

• 영문명: Two Cases of Miller Fisher Syndrome without Ataxia
• 발행기관: 대한소아신경학회
• 저자명: 주미(Mi Ju) 이계향(Kye Hyang Lee) 김숙영(Sook Young Kim)
• 간행물 정보: 『Annals of Child Neurology(구 대한소아신경학회지)』대한소아신경학회지 제15권 제2호, 205~210쪽, 전체 6쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2007.11.30

국문 초록

저자들은 감염성 질환 후에 발생한 급성 외안근마비, 심부건반사 소실을 주소로 내원한 Miller Fisher 증후군이 의심되는 환아에서 항 GQ1b 항체를 측정하여 진단에 활용하여 항체 양성 환아 1례와 음성 환아 1례를 각각 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

영문 초록

A classic triad of acute external ophthalmoplegia, areflexia and ataxia characterizes Miller Fisher syndrome(MFS). Diagnosis is based on clinical findings and supported by two laboratory findings; CSF albuminocytological dissociation and serum anti-GQ1b IgG antibody testing. Anti-GQ1b antibody is a key factor in the pathogenesis of Miller Fisher syndrome and a useful marker in laboratory diagnosis. Here we report 2 cases with Miller Fisher syndrome without ataxia, whose major symptom was acute external ophthalmoplegia. Case 1 was associated with preceding Epstein-Barr virus infection and negative anti-GQ1b antibody. Case 2 was positive for the anti-GQ1b antibody. Both received intravenous immunoglobulin and fully recovered within 2 months after the onset of disease.

목차

서론

증례

고찰

요약

References

키워드

Miller Fisher syndrome Anti-GQ1b antibody