Feasibility of the diagnosis of osteoporosis with broadband reflection/backscatter loss in bovine cancellous bone

• 발행기관: 강원대학교 기초과학연구소
• 저자명: Kang Il LEE
• 간행물 정보: 『기초과학연구』제19집, 1~12쪽, 전체 12쪽
• 주제분류: 자연과학 > 자연과학일반
• 파일형태: PDF
• 발행일자: 2008.12.30

영문 초록

The frequency-averaged broadband reflection/backscatter loss (BRBL) from 0.5 to 1.5 MHz was introduced for the diagnosis of osteoporosis. Correlations of speed of sound (SOS), broadband ultrasonic attenuation (BUA), integrated reflection coefficient (IRC), and BRBL with apparent density were investigated by using previously published measurements in bovine cancellous bone in vitro. SOS exhibited a significant correlation with density (r = 0.64). A comparable correlation was observed between BUA and density (r = 0.53). IRC was moderately correlated with density (r = 0.70). A moderate correlation was also found between BRBL and density (r = 0.73). The multiple regression model including all four ultrasonic parameters resulted in a significant improvement for predicting density (r = 0.83). This study suggests that BRBL may be a useful adjunct measurement in combination with the established ultrasonic parameters such as SOS and BUA for multifeature characterization of bone.

목차

Abstract

1. Introduction

2. Materials and Methods

3. Results and Discussion

4. Conclusion

5. Acknowledgment

6. References