우울증 가족력에 따른 주요 우울장애 환자의 특성

• 영문명: Characteristics of major depressive disorder according to family history of depression:A CRESCEND-K (Clinical Research Center for Depression in Korea) study
• 발행기관: 한국역학회
• 저자명: 정승희(Seunghee Jeong) 임현우(Hyeon Woo Yim) 정영은(Youngeun Jung) 조선진(Sunjin Jo) 전태연(Taeyoun Jun) 정성원(SungWon Jung) 이민수(Minsoo Lee) 김재민(Jaemin Kim)
• 간행물 정보: 『한국역학회지』韓國疫學會誌 第30卷 第2號, 272~280쪽, 전체 9쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2008.12.31

영문 초록

Purpose: People with a family history of mood disorder are more likely to have depression. This study compared the characteristics of non-psychotic major depression disorder according to family history of depression. Method: Subjects were total of 817 persons recruited for the CRESCEND-K multicenter trial. Characteristics of depression and suicide history of patients with and without a family history of depression were assessed. Family history was determined through self-report. Results: Of 817 participants, 12.4% had a positive family history of depression. Those with family history of depression reported an earlier age at onset of MDD, and more psychiatric comorbidity. Severity of depression and anxiety were not different according to family history of depression. There were no difference in attempted suicide history, number of attempted suicide and age at onset of 1st attempted suicide according to such a family history. Conclusion: Patients with family history of depression reported earlier onset of MDD and more history of psychiatric comorbidity.

키워드

Major depressive disorder Family history