한약재로부터 추출된 물질의 면역 효과

• 영문명: Effect of material isolated from chinese medicinal herb on immune system
• 발행기관: 고려대학교 보건과학연구소
• 저자명: 김경임(KyungIm Kim) 김경미(KyungMi Kim) 강창수(ChangSu Kang)
• 간행물 정보: 『보건과학논집』保健科學論集 Vol.30 No.2, 51~57쪽, 전체 7쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2004.12.01

영문 초록

  This study is focused on clarifying the functional aspects of the extracts from Gleditsiae spina, which has been used as one of the favorite chinese medicinal herbs for a long time. To detect the possible effects of Gleditsiae spina extracts on the immune system of mice, macrophage lysosomal enzyme activity and anti-complementary activity were calculated in semi-vivo. Among different solvent extraction, hot water extract of Gleditsiae spina showed higher macrophage lysosomal enzyme activity and anti-complementary activity than others.
  During mass extraction, low molecular weight fraction was removed by using MtOH extraction of Gleditsiae spina. High molecular fweight raction was obtained by hot water extraction and the EtOH precipitation. Fraction GS-1, showing 212% macrophage lysosomal enzyme activity and 81.5% anti-complementary activity, consisted of 38.8% carbohydrate, 21.1% protein and 10.1% uronic acid. Besides no lethal toxicity was observed in GS-1.

목차

Abstract
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과 및 고찰
Ⅳ. 결론
참고문헌

키워드

Gleditsiae spina macrophage lysosomal activity anti-complementary activity