학술논문
Finding drug candidates against melioidosis using in-silico docking with the crystal structure of transketolase
이용수 7
- 영문명
- 발행기관
- 대한약학회
- 저자명
- PARK Jimin YEO Sang A LEE Daeun KIM Mi-Sun SHIN Dong Hae
- 간행물 정보
- 『춘계총회 및 학술대회』(2015년), 533~533쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2015.04.24
0원
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- Sustained release Melt Extruded formulations using Eudragit RSPO and RLPO and content uniformity by FT-IR chemical imaging
- Population pharmacokinetic modeling of midazolam in healthy volunteers : evaluation for drug-drug interaction
- Effects of regulatory nuclear receptor (CAR, HNF4α and PXR) genetic polymorphisms on stable warfarin doses in patients with mechanical cardiac valves
- Application of Advanced Compartmental Absorption and Transit model for prediction of human pharmacokinetic(PK) profile uisng preclinical in-vitro and in-vivo studies
- Oxidative C7-Acylation of Indolines with Aldehydes or Alcohols under Palladium Catalysis
- New cytotoxic sesquiterpenoids from siegesbeckia glabrescens
- Eriobotryae Folium improved inflammatory response through an oxidative stress and advanced glycation endproduct-meidated pathway in the liver of type 2 diabetic db/db mice
- Taming the chemical reactivity and selectivity : Known and unknown paths (and somewhere between)
- Effects of AGS to stress caused by climate change
- Evaluation of questions from Cybercondriacs related to drug information and suggestion of providing evidence-based answer
- PEGylation effect of poly(amidoamine) dendrimers on cytotoxicity in hippocampal neuronal cells
- Effects of geniposide on hepatocytes undergoing epithelial-mesenchymal transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways
- Metabolomic application for MS based flavonoid research
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl) phenol Isolated from Butanol Fraction of Cordyceps bassiana
- Para-methoxymethamphetamine (PMMA) induces neurotoxicity and memory impairments in mice
- Characterization of the auditory electrophysiological responses in rat with salicylate-induced tinnitus
- IRAK4 as a therapeutic target of innate immunity-imbalanced acute liver injury by chlorogenic acid
- Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter via nuclear receptor ERRγ in SH-SY5Y cells
- Anti-inflammatory Activities of Gouania leptostachya Methanol Extract and its Constituent Resveratrol
- Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice
- The stereoisomers of crizotinib differentially induce change in the morphology of cancer cells
- Radiation human exposure and cancer risk assessment in cosmetics
- Evaluation of chemosensitivity using patient-derived xenograft model
- Ginseng total saponins induces the cardioprotection against ischemia/reperfusion injury
- Induction of integrin signaling by steroid sulfatase metabolism in HeLa cells
- Selective C–H Cyanation of Indolines and Indoles with Easily Accessible Cyano Source under Rhodium Catalysis
- Selective C–H Allylations of Indolines and Indoles with 4-Vinyl-1,3-Dioxolan-2-One under Rhodium Catalysis
- Chiral separation of evodiamine in the biological sample by HPLC
- Structure ensemble based virtual screening discovered new inhibitors of tyrosinase
- Preparation and evaluation of oral disintegrating film containing local anesthetic agent, Lidocaine
- Determination of drometrizole trisiloxane by LC-MS/MS and application to an in vitro dermal absorption study
- The Misuse or Abuse of Stimulant Medications for Attention-Deficit/Hyperactivity Disorder (ADHD) in Adolescents and Adults
- The potent medicinal plants, species of Lycopodiopsida, as a therapeutic agent for non-alcoholic fatty liver disease
- Influence of MRP2 C24T genetic variant on the pharmacokinetics of Valsartan
- Alleviation of ischemia and reperfusion-induced liver injury by SPA0355
- Increased neural stem cell proliferation by quercetin-3-O-glucuronide
- Preparation and physicochemical characterization of cocrystal comprising celecoxib and tramadol hydrochloride for improved intrinsic dissolution rate
- Stereoselective total synthesis of 1-deoxygalactonojirimycin and research on total synthesis of 1-deoxyidonojirimycin via chiral 1,3-Oxazine
- Design, synthesis, and biological evaluation of small molecule as hsp90 inhibitor
- Screening of Novel Monoamine Oxidase Inhibitors from Extracts of Lichens with Ethyl Acetate
- Drug development targeting Pin1-catalyzed conformational changes in cancer and Alzheimer’s Disease
- Beneficial effects of Humulus japonicus extract on hyperlipidemia and fatty liver induced by high-fat diet obesity
- Anti-cancer effect of (E)-4-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol on colon cancer cell growth by activation of DRs and inhibition of STAT3/NF-κB pathways
- Mitochondrial alteration and AMPK activation in NRF2-silenced human cancer cells
- Neuroprotective effects of WSY against lipopolysaccharide-induced neuronal damage
- 15-deoxy-Δ12,14-prostaglandin J2-induced cell apoptosis through ROS-mediated mechanism in gastric cancer cells
- Hydroquinone suppresses expression of IFN- β via AKT regulation
- Citrus unshiu peel extract protects cultured rat cortical neurons from beta amyloid-induced neurotoxicity
- Neuroprotective effects of labm99 on ischemia/reperfusion injury through inhibiting ASK1-JNK-p38 signal pathway
- Facile and Inexpensive microfluidic array chips for the detection of DNA/RNA pathogens
- Preparation of chitosan coated alginate-Bee Venom nanoparticles
- Quantitative analysis of sphingomyelin by high-performance liquid chromatography after enzymatic hydrolysis
- Idebenone, an ANO1/CaCC inhibitor found by High-throughput screening, has potential for use in cancer therapy
- In-silico search for putative drug candidates against melioidosis based on the crystal structure of sedoheptulose-7-phosphate isomerase
- Directions in convergent and creative pharmacy human resource development in terms of academia - focused on neuropharmacology
- Oxidative Allylation of Aromatic and α,β-Unsaturated Carboxamides with Allylic Carbonates under Ruthenium Catalysis
- Eco-friendly synthesis and catalytic activity of catechin-capped gold nanoparticles
- Quantitative analysis of trans-Anethole in Fennel seed by GC/MS
- HPLC-UV analysis of the ortho-phthaldehyde in disinfectant for quality control
- Lipid-Enveloped ‘Smart’ Polyelectrolyte Complex Nanoparticles for Highly Effective Combination Chemotherapy
- Dysfunctioned Tau by direct interaction with SOD1 G93A disrupts microtubule structure in axon
- Reprogramming of human fibroblasts to neuronal precursor cells with plant stem cell-derived Molecule
- Effect of sarpogrelate on high-fat diet-induced nephropathy
- Melatonin effectively enhances aging indices by activating helper T cell signaling
- Understanding of visible particulates and foreign insoluble matter test in biopharmaceutical product for international regulatory harmonization
- Effect of isoflavones on the lysosome and TFEB activity
- Connecting the present and the future, Hanmi’ s R&D strategy
- The March first independence movement of Chosun Pharmacy School students
- Inhaler Generic Development case - Fluterol Inhalation powder
- Compound-14 isolated from Acanthopanax Root Bark inhibits inflammation by modulate the expressions of inflammatory marker via inactivation of MAPK pathway in murine macrophages
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- Chromatographic enantiomer separation and determination of chemical and optical purity of α-amino acids and methyl esters as fluorenylmethoxycarbonyl derivatives with fluorescence detection
- Anti-tumor activity of coptisine in human lung cancer cells by modulating Snail signaling pathway and epithelial-mesenchymal transition
- Isolation and structural determination of new diketopiperazine alkaloid from a marine-derived fungus Penicillium sp.
- A study on relationship between morphological characteristics and drug information of solid oral dosage forms in korean domestic market
- Effects of ganglioside on default mode network connectivity in individuals with subjective cognitive impairment
- Neuroprotective effect of silibinin on the acute Parkinson's disease mouse model is mediated by modulating astrocyte activation
- β-lapachone inhibits lung metastasis of colorectal cancer by inducing apoptosis of CT26 cells
- Protective effects of rutaecarpine on tert-butylhydroperoxide-induced toxicity in HepG2 by up-regulation of heme oxygenase-1 expression
- The orphan nuclear receptor RORα enhances transcription of Retnla in the mouse kupffer cells
- Isoguaiacins, arylnaphthalene types identified as novel potent estrogenic signaling molecules from Larrea nitida
- Cuttlebone extract induces the production of pro-inflammatory cytokines in macrophages
- Developing renal dose adjustment module in clinical decision support system for clinical practice
- Korean red ginseng inhibits hemodynamic dysfunction in guinea pig heart
- 15-Hydroxyeicosatetraenoic acid increases adipogenesis in 3T3-L1 adipocytes by promoting early adipogenic differentiation
- Plasminogen affects the kinetics of PrP amyloid formation
- Secondary metabolites produced by an endophytic fungus, Harpophora oryzae
- Education for global pharma in the future society
- Charaterization of the role of tyrosine-phosphorylated signal transducer and activator of transcription 3 (pYSTAT3) on liver regeneration using a phosphorylation site-specific intrabody
- Current status and future prospects of Hanmi’ s global innovative drug development
- Faculty performance evaluation method in College of Medicine, Chungnam National University
- Effects of (-)-sesamin on chronic stress-induced memory impairment in mice
- Anti-diabetic and Anti-Alzheimer’s disease activities of Angelica decursiva
- An Analysis of Pharmacy Volunteer Work in the Region without Separation of Dispensary from Medical Practice in Korea
- Panel Discussion : Win-Win Strategies in the Pharmaceutical Industry
- Fabrication and characterization of piroxicam loaded nanospheres to enhance the solubility and bioavailability via electrospraying technique
- Current status of Antibody Drug Conjugate (ADC) regulation in Korea
- The role of prohibitin 1 as a host partner of Vibrio vulnificus RtxA1 toxin
- Analytical strategies for Quality Assurance/Quality Control of biotherapeutic glycoproteins
- Portulaca oleracea L. Protects Human Skin Keratinocytes Against Free Radical-induced Oxidative Damage though Up-Regulation of HO-1/Nrf2 Expression
- Anti-oxidative and Anti-inflammatory Phenolic compounds from the stems of Carpinus tschonoskii
- Protein tyrosine phosphatase 1B (PTP1B) inhibitor from the leaves of Smilax china L.
- Anti-cancer effect of (E)-4-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol on colon cancer cell growth by activation of DRs and inhibition of STAT3/NF-κB pathways
- Identification of EAM-2201, a synthetic cannabinoids, and its metabolites in human liver microsomes using liquid chromatography-high resolution mass spectrometry
- A new neolignan glycoside from the roots of Coix lachryma-jobi var. mayuen Stapf
- Alcohol Use Patterns of College Students in Korea
- Glycine-bearing celecoxib derivatives is a potential colon-specific mutual prodrug acting on an anti-inflammatory target, NF kappaB
- Buphedrone induces conditioned place preference via dopaminergic system
- Effect of Diltiazem, A moderate CYP3A4 inhibitor, On the pharmacokinetic parameters of Tamsulosin
- Protective effects of Genipin on gastric cancer cell
- Neuroprotective Effect of KPE-12 on Glutamate-induced Oxidative Cytotoxicity in HT22 cells
- A novel metformin derivative inhibits proliferation and invasion of triple-negative breast cancer cells
- Inhibition of Mitochondrial Fission Ameliorates the Pathogenesis of Alzheimer's Disease
- Neuroprotective and anti-neuroinflammatory effects of KHUR-EcPr against lipopolysaccharide-induced neuronal damage
- The comparison between heat or microwave 70% EtOH Extracts of the heartwood of Caesalpinia sappan for anti-inflammatory effects on LPS-induced macrophages
- Coadministration of Hedera helix L. extract enabled mice to overcome insufficient protection against influenza A/PR/8 virus infection under suboptimal treatment with oseltamivir
- LPS-stimulated secretomics analysis in endothelial cells to identify a new biomarker for sepsis
- The change of genetic expression in diabetic complication: effect of Korean red ginseng
- Ethyl acetate fraction from Physalis alkekengi fruit exerts potent antioxidant effects through Nrf-2/HO-1 pathway in BV2 microglial cells
- Establishment of HPLC analytical method for marker compounds from the roots of Gastrodia elata Blume
- Dependence potential of 5-APB, lisdexamfetamine, and phenazepam in rodents
- Targeting both EGFR and MET by butein overcomes gefitinib-resistant non-small cell lung cancer growth
- An Isolated Natural Compound, KJB-2, Negatively Regulates Spleen Tyrosine Kinase by Up-Regulating Src-Like Adaptor Protein
- Modulation of CD4+ T cell differentiation by benzoxazole derivatives
- Antioxidant effect of Selenigella tamariscina methanol extract on impairments induced by scopolamine in rats
- In vitro simulation of food effect on dissolution of BCS class III drug: The correlation of in vitro dissolution and in vivo absorption
- Catalase protects high-fat diet-induced early liver injury
- Comparison on tooth stain prevention effect of SAPP-contained mouthwash and others
- Antitumor activity of myriocin, a sphingolipid biosynthesis inhibitor, and its mechanism in melanoma mice
- Role of IL-32alpha as an anti-inflammatory cytokine in MOG-induced experimental autoimmune encephalomyelitis
- Structural mechanism of ergosterol regulation and antifungal resistance by fungal sterol transcription factor Upc2
- Ilex paraguariensis increases capability to resist starvation stress in Drosophila
- Intramuscular administration of novel SLNs-loaded dual-reverse thermosensitive nanomicelle with sustained release and reduced toxicity
- The evaluation of communication skills on medication counseling perceived by multicultural population: focused on the service provided by pharmacists
- In vivo gastroprotective effect along with pharmacokinetics, tissue distribution and metabolism of isoliquiritigenin in mice
- In vitro activity of (-)-deoxypergularinine against Mycobacterium tuberculosis strains
- Potent and selective inhibition of sarpogrelate and its active metabolite, M-1, on the Human UDP-glucuronoslytransferase 1A4 activity
- Graphene oxide functionalized with poly(2-dimethylaminoethyl methacrylate) for efficient siRNA cellular delivery
- Shear stress enhances Ca2+ spark occurrence in rat ventricular myocytes via the activation of NADPH oxidase
- Regulation of CYP19A1 aromatase expression in breast cancer microenvironment
- Pharmacological talents of pharmaceutical industry in the future
- Effect of endothelial nitric oxide synthase by impressic acid isolated from Acanthopanax koreanum in endothelial cells
- Regulatory effect of glycyrol in CYP1A1 and 2C9 in human liver microsomes
- Dapoxetine decreased the excitability of small dorsal root ganglion neurons
- Preclinical evaluation of immunogenicity and immunotoxicity of stem cell therapy
- HPLC analysis for sesonal variation and anti-Oxidative activities of isolated components by Artemisia iwayomagi Kitamura
- Autocrine stimulation of IL-10 is critical to the enrichment of IL-10-producing CD40hiCD5+ B cells
- Roles of community pharmacists for pharmaceutical safety management
- Development of standard criteria for the quality evaluation of The Gentianae Macrophyllae Radix by TLC and HPLC
- Tonsil-derived mesenchymal stem cells: its therapeutic potentials and application
- The roll of hospital pharmacist on clinical service
- CAC-0982 suppresses mast cell activation and IgE-mediated allergic responses in mice
- Synthesis and evaluation of novel 1-methylcarbapenem derivatives with imidazoline
- Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced beta-cell damage and the development of type 1 diabetes
- Combination therapy using CD133-targeted immunoliposomal gemcitabine and bevacizumab for glioblastoma
- Risk-based monitoring in clinical research – merits and demerits
- Dose-independent ADME properties and tentative identification of metabolites of a-mangostin from Garcinia mangostana in mice by automated microsampling and UPLC-MS/MS method
- Proton-mediated inhibitory mechanism of ANO1
- Anticonvulsive potential of glutathione peroxidase-1 against convulsive behaviors induced by cocaine
- A Novel compound from Antartic lichen restores cognition via suppression of inflammasome and BACE1 expression in Alzheimer’s disease mice
- Sulfur-based certification of protein candidate reference materials using isotope dilution ICP-MS
- Dual characterization of electroosmotic volume flow through skin and the modulation of ketoprofen flux using polyethyleneimine
- Inhibition of advanced glycation endproducts formation by Korean thistle, Cirsium maackii
- Domestic and international trends and the need for cosmetic GMP
- The development of Sarpogrelate Hydrochloride Controlled-Release Tablet(DP-R202), a selective 5-HT2A antagonist
- Oligonol supplementation modulates plasma volumeand osmolality and sweating after heat load in humans
- Pharmacokinetic study in disease animal model
- Development of Hot-Melt Extruded formulations with pressurized carbon dioxide
- Inhibitory effects on gstric lesions of Genipin
- A Study on Physiological Activity and Antioxidative Activity of Extracts from Parts of Angelica polymorpha Maxim
- Chondroprotective effect of natural products in articular cartilage in vitro and in vivo
- Organic Anion-Transporting Polypeptide 1B1-mediated drug interaction between Valsartan and Gemfibrozil in rats
- Repositioning of Prickly Pears grown in Jeju Island for treatment of perimenopausal symptoms
- Current status of bio-drug R&D and the role of New Drug Development Center in Osong Medical Innovation Foundation
- Multiresidue method for the quantitation of 20 pesticides in aquatic products
- Kaempferol, a dietary flavonoid, ameliorates acute inflammatory symptoms in gastritis, pancreatitis, and abdominal pains
- Korean red ginseng inhibits myocardial toxicity by doxorubicin
- Nrf2 regulates AhR activity, which contributes to cell survival
- Modification of potent anticancer Vatalanib; The discovery of Alkylsulfonylanilinopyridazines and its antitumor activity
- The effects of chronic social defeat stress on emotional behaviors and epigenetic regulation in mice
- Preparation and characterization of MHY 498 loaded Solid Lipid Nanoparticles (SLNs) in the treatment of hyperpigmentation
- The Ameliorative effect of Quercus acutissima on DSS-induced colitis in mice
- Effects of ethanol extract from RCBH-GP on affective disorders in animal models and its clinical application
- Lack of association between OCT2 C602T genetic variant and the pharmacokinetics of Lamivudine in healthy korean subjets
- Anti-cancer activity of zinc ion-sustained releasing ZnO chips
- Anti-oxidant and anti-inflammatory effect of capillarisin involved in Nrf2/ARE-mediated defense mechanism
- Evaluation of protein formulation and its viscosity with DSC, DLS, and microviscometer
- Mode Of Inhibition Of AXL Tyrosine Receptor Kinase by a heteroaryl Substituted Triazole Compound
- Pharmacokinetics and therapeutic efficacy of piroxicam, a long acting non-steroidal anti-inflammatory drug, after intra-articular injection in osteoarthritis-induced rats
- Exogenous 8-oxo-dG prevents high fat-induced liver injury through enhancing mitochondrial biogenesis
- Identification and development of NamPT inhibitors as a synthetic lethal agent for NAPRT1-deficient lung cancers
- Resveratrol inhibits collagen-induced platelet stimulation through suppressing NADPH oxidase and oxidative inactivation of SHP-2
- Design, synthesis and biological evaluation of 1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indole-3-carboxamide analogs as anti-TNBC agents
- Preparation of modified mRNA by in vitro transcription (IVT) for long-term protein expression
- 4-O-methylhonokiol inhibits cell growth and induces apoptosis in non small cell lung cancer cell lines
- Transport characterization of flavonoids in conditionally immortalized rat brain capillary endothelial cell lines
- KPS-27 Suppressed RANKL-induced Osteoclast Formation in vitro
- Requirements to be considered in the LIMS optimization process
- Antioxidant and anti-melanogenesis activities of fruit extract of Indonesian Lai, Durio kutejensis [Bombacaceae (Hassk) Becc]
- Effects of apigenin and synthetic flavones on senescence-associated secretory phenotype in bleomycin-induced senescence in BJ fibroblasts and in vivo aged rats
- Advancement of pharmacy management and case
- A gelatin microparticle-containing self-microemulsifying formulation for enhanced dissolution and oral absorption of dutasteride
- A novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis through downregulation of Akt in human lung cancer cells
- The effect of local anesthetics on the protein clustering of neuronal membranes
- 3-Methylcholanthrene leads to phenotypic changes associated with epithelial-mesenchymal transition in liver cells
- PTP1B inhibitory constituents from the aerial parts of Tradescantia spathacea Sw
- Pomolic acid inhibits invasion of breast cancer cells through the suppression of CXC chemokine receptor type 4 expression
- Green gold nanoparticles synthesized using earthworm extracts and the reinforcing effect on anticoagulant activities of heparin
- Pathogenesis-related proteins (PRP) from a dropwort play a role in regulating toll-like receptor-dependent downstream signal pathway
- Attenuation of dbcAMP-induced Bad phospholylation in PC12 cells
- Capiilary gel electrophoresis-on-a-chip of partly and fully PEGylated poly(amidoamine) dendrimers
- Transient receptor potential vanilloid type 1 modulate morphine reward in the nucleus accumbens
- Toxicological study for hydrogen cyanide, carboxyhemoglobin, ethyl alcohol and drug concentrations in postmortem blood specimens of the fire related fatalities
- Health benefit of phlorotannins from edible brown algae, Ecklonia
- Stability of glutamate carboxypeptidase II, a glutamate synthesizing enzyme, is regulated by acetylation
- Design and synthesis of 1,2,3,4-Tetrahydroquinoline-2-carboxylic acid N-(substituted) phenylamide derivatives as potential NF-kB inhibitor
- Inhibition of Wnt/β-catenin pathway by dehydrocostus lactone and costunolide in colon cancer cells
- A ring-truncated deguelin analogue induces apoptosis and anti-angiogenesis in non-small cell lung carcinoma cells
- Development and Evaluation of New Immediate-Release Dosage Form for Complex Migraine
- Distinct contact dynamics of lytic and non-lytic interactions between natural killer cells and tumor cells
- δ-Tocopherol prevents MGO-induced apoptosis by inhibiting apoptotic signaling cascades in HUVECs
- Toll-like Receptor-mediated Sestrin2 Gene Regulation by AP-1, Nrf2, and the Ubiquitin-Proteasome System in Macrophages
- - IP-R&D strategy case - Companion Diagnostics(CDx) technology development and set up R&D direction through patent analysis
- In Vitro Selective Inhibition of Human UDP-Glucuronosyltransferase (UGT) 1A4 by Finasteride, and Prediction of In Vivo Drug–Drug Interactions
- In vitro and in vivo characterization of novel anti-AMF human monoclonal antibody for cancer therapy
- Structure ensemble based virtual screening discovered new inhibitors of tyrosinase
- Aminopyridinol derivatives inhibit serotonin- and MDA-MB-231 human breast cancer-induced angiogenesis
- Kaaempferol suppresses collagen-induced platelet activation through inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation
- Solanum tuberosum L. cv Hongyoung extract inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice
- Pharmacotherapy for the Treatment of Rheumatoid Arthritis: the Updates of New Guidelines and Recently Approved Drugs
- Metabolomic profiling of valproic acid-induced rat model of autism spectrum disorders using 1H NMR spectral analysis
- Synthesis and biological activity of tricyclic derivatives containing a phenyl ring
- Enhancement of Pharmacokinetic Profile and Antitumor Activity of Irinotecan using Polypeptide-based Block Ionomer Complex Micelles
- Factors affecting medication adherence in patients with diabetes mellitus using the Korea Health Panel (KHP)
- Studies on the mehanism of inhibition of serum and glucocorticoid-inducible kinases (SGKs) by a pyrrolopyridine derivative
- Evaluation of antioxidants in protein formulation against oxidative degradation using various biophysical analysis methods
- Development of laboratory monitoring alert system of hyperkalemia related to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
- Identification of anti-obesity compounds based on mechanisms
- Two new compounds from the grains of Echinochloa utilis (Barnyard Millet)
- Efficient DNA vaccination using chemoattractant loaded microsphere/polyplex releasing multi-layered microneedle
- Alcohol induced hyper-acetylation analysis in mouse hepatoma cell using Mass spectrometry-based proteomics
- Glycosylation of recombinant CTLA4Ig expressed in transgenic rice cells
- Structure-based drug design of Hsp90 inhibitors and their anti-proliferative effects against cancerous diseases
- The inhibitory effect of SMB-6 on Rotenone induced endoplasmic reticulum stress and cell death in SH-SY5Y cells
- Activation of NOX2 induces invasive phenotype in colon cancer cells through overexpression of MMP-7
- Hyperphosphorylation of tau in hippocampus in dab-treated mice might be associated with cognitive impairment
- A polymeric colon-specific prodrug releasing 5-ASA and benzocaine ameliorates TNBS-induced rat colitis
- 5-Aminosalicylic acid activates AMPK: an implication in anti-colitic activity of the anti-inflammatory drug
- Design and synthesis of heat shock protein 90 inhibitors to impair the growth of non-small cell lung cancer (NSCLC)
- A multi-class analytical method for screening and confirmation of veterinary drug residues in fishery products based on liquid chromatography coupled to tandem mass spectrometry
- Coumarins from Angelica decursiva inhibit lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells
- Stereoselective total synthesis of (+)-castanospermine
- Cristacarpin inhibits endotoxin-induced inflammation in murine macrophages
- Analysis of the mission and goal of pharmacy education
- Development and evaluation of orally disintegrating tablet by inclusion complex
- Effects of regulatory nuclear receptor (CAR, HNF4α and PXR) genetic polymorphisms on stable warfarin doses in patients with mechanical cardiac valves
- The Improving effect of Cucumis melo on atopic dermatitis in vivo
- A novel PPAR pan agonist MHY2013 improves insulin-resistance and dyslipidemia in db/db mice
- 31 Structure-based drug design of Hsp90 inhibitors and their anti-proliferative effects against cancerous diseases
- Bidirectional actions of hippocampal Zn2+ signaling in cognition: its involvement in amyloid-β-induced cognitive decline
- Antimelanogenic effect of 2-methoxyphenyl-1-benzimidazole
- Critical role of AMPK / FoxO3 axis in globular adiponectin-induced cell cycle arrest in hepatic cancer cell
- The anti-inflammatory effect of Luteolin in LPS-mediated macrophage
- Glutathione peroxidase 1 deficiency attenuates Concanavalin A-induced hepatic injury by modulation of T-cell activation
- A Aovel [3+3] Annulation Approach to Indolizines from the MBH Allyl Bromides
- Tacrolimus-encapsulated porous poly(lactic-co-glycolic acid) microspheres for treating bleomycin-induced pulmonary fibrosis
- Signal transduction underlying the inhibitory mechanism of Fluoxetine on Electrical field stimulation response in rat ileal smooth muscle
- Species difference elucidation of 11β-hydroxysteroid dehydrogenase 1 through ensemble and induced fit docking studies
- Improved pharmacokinetics and brain delivery of resveratrol from N-Trimethyl chitosan-g-palmitic acid surface modified solid lipid nanoparticles
- Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25-35 neurotoxicity
- Nitric oxide-releasing chitosan films for enhanced antibacterial activity and in vivo wound healing efficacy
- Prognostic gene signatures in pediatric medulloblastoma
- Wound healing effect of the butanol fraction from Hydnocarpi Semen crude extract in ulcer injury of mice
- Validation of S-zaltoprofen in rat plasma by HPLC
- Process control strategy in biopharmaceutical manufacturing
- The association of CaSR rs1042636 polymorphisms with cinacalcet effectiveness in ESRD patient on dialysis
- The role of exercise-induced hormones in metabolic regulation
- A novel compound F : its antiplatelet effect via suppressing PKC theta and Akt phosphorylation
- Smoking has significant effects on the pharmacokinetic parameters of Tolperisone
- 6-O-veratroyl catalpol suppressed proinflammatory cytokines and CCL-5 chemokine via Erk 1/2 and STAT3 in human monocytic cells
- Cytotoxic and DNA topoisomeraes Ⅰ and Ⅱ inhibitory activity of constituents from Plantago asiatica L.
- New alkaloids from roots and rhizomes of Veratrum nigrum L.
- Understanding the pharmacokinetic rationale for the dual-release formulation using bi-layer tablet of sarpogrelate hydrochloride
- Connecting the present and the future, Hanmi's R&D strategy
- History of Korea Drug Research Association (KRDA)
- The critical role of negative feedback regulators in inflammation and host defense
- Stereoselective total syntheses of (+)-radicamine B and (-)-codonopsinine via chiral anti,syn-oxazine
- Survival and maintenance of regulatory T cells require the kinase TAK1
- Globular adiponectin inhibits LPS-induced inflammasome activation via induction of autophagy in macrophages
- An orally available multi-kinase inhibitor dovitinib (TKI258) enhances BMP-2-induced osteoblast differentiation
- Role of heme oxygenase-1 in inhibition of dendritic cell functions by Saururus chinensis extract
- YP754 inhibits adipocyte differentiation via downregulation of PPAR-gamma in adipocytes
- Synthesis of Aminocyclopentitol Analogues via Stereoselective Amination of Cyclic Polybenzyl Ether with Chlorosulfonyl
- Synthesis of chlorogenic acid derivatives possessing pyridine as NF-kB potential inhibitors
- Effects of terminal N-acetylglucosamine of egg-white ovalbumin N-glycans on the IgE production and Th2 cytokine secretion
- Association study of SNPs at 3’ untranslated region of prion protein gene and sporadic CJD
- A new pregnane glycoside from Cynanchum wilfordii
- Antiplatelet effect of GE extract by high hydrostatic pressure and enzymatic hydrolysis
- Suppression of Th2-chemokines production by crocin via blocking of ERK-MAPK/NF-κB/STAT1 signaling pathways in TNF-α/IFN-γ-stimulated human epidermal keratinocytes
- Grape seed extract modulates melanogenesis and antioxidant defense system in B16 melanoma cells
- MiR-130a and miR-495 synergistically regulate cell proliferation and tumor angiogenesis through modulation of RUNX3
- In-vitro study of Novel Active Ingredient for Dentin Hypersensitivity Toothpaste
- A novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis through downregulation of Akt in human lung cancer cells
- Anti-cancer activity of KTH-13-amine monophenyl from Cordyceps bassiana
- A study on cardiac injury by isoproterenol: effect of red ginseng
- Synthesis and biological activity of quinazolone derivatives containing a 2-phenyl ring
- Antioxidant and anti-inflammatory activity of N-((3,4-dihydro-2H-benzo[h]chromen-2-yl)methyl)-4-methoxyaniline in LPS-induced BV2 microglial cells
- Flavonoid constituents from n-butanol fraction of the aerial parts of Agrimonia pilosa Ladeb
- Antidepressant-induced upregulation of neurotrophic factors and activation of their signaling pathway
- Duel function of a novel compound E on platelet-derived growth factor-induced vascular smooth muscle cells
- Microcystin-Leucin-Arginine Induces Hippocampal Excito-neurotoxicity and Memory Impairments in Mice; Involvement of Oxidative Stress
- Discovery of mutant-selective EGFR tyrosine kinase inhibitors for EGFR T790M
- Novel free-flowing fenofibrate-gelatin microcapsules with improved aqueous solubility : Preparation, physicochemical characterization and pharmacokinetics in rats
- Kinetics and mechanism of the liposomal transport of doxorubicin: the path to a mechanistic model for evaluation of in vitro drug release
- Preclinical assessment of toxicity and toxicokinetics of piroxicam after intra-articular injection in normal rats
- Acerogenin A, a natural compound isolated from Japanese folk medicine Acer nikoense Maxim, prevents oxidative stress-induced neuronal cell death through Nrf2-mediated heme oxygenase-1 expression
- Screening of bioreducible CBA-amine polymers for the effective gene delivery
- SESN2 inhibits ROS-mediated HIF-1a accumulation in colorectal cancer cells
- Synthesis and Biological Evaluation of Chemical Probes Targeting Hypoxia-Inducible Factor (HIF)-1α/ Malate Dehydrogenase 2
- Therapeutic effect of cilostazol, a phosphodiesterase III inhibitor, on chronic kidney disease
- Role of SPCIP4 in epithelial mesenchymal transition of A549 lung cancer cells
- Chemotherapeutic potential of Hsp90 and biological evaluation of a novel Hsp90 inhibitor
- Secondary metabolites produced by an endophytic fungus, Harpophora oryzae
- Determination of urazamide in pharmaceutical preparations by reverse phase liquid chromatography with room temperature ionic liquids
- Overview of polmacoxib (AcelexⓇ): Newly approved drug for osteoarthritis
- Development of SIVEXTRO (tedizolid phosphate), A new oxazolidinone antibiotic
- Enhanced therapeutic efficacy of budesonide in ulcertaive colitis with enzyme/pH dual-sensitive polymeric nanoparticles
- Theme Presentation : Current issues and status in the pharmaceutical field
- Simultaneous determination of three phytosterols, β-sitosterol, campesterol, and stigmastrerol, in rat plasma and tissues byLC-MS/MS and its application to a pharmacokinetic study
- From finding to filling the gaps among the real and regulation-driven toxicological approaches for antibody-drug conjugate development
- Phentermine, an anti-obesity drug, induces the conditioned rewarding effects via the activation of PI3K/Akt signaling pathway in the nucleus accumbens
- The Patents of material, the beginning of a new opportunity
- Directions in convergent and creative pharmacy human resource development in terms of academia - focused on clinical pharmacy area
- History of department of pharmacy, Seoul National University Hospital
- Inhibition of lung inflammation by Acanthopanax divaricatus var. albeofructus and the constituents
- Therapeutic effects of silibinin on the MPTP-induced Parkinson's disease model
- Synthesis and Biological Evaluation of Hydroxamate Amides as HDAC Inhibitors
- A study on hemodynamics of ginseng total saponins in reperfusion damage
- Interspecies pharmacokinetic scaling of FL-05 based on animal data
- A brief review on the establishment process of newly implemented 6-year pharmacy education program in Korea
- Transcriptional regulation of cancer stem cell marker CD133 by p53
- Genetic inhibition of ceruloplasmin potentiates neurotoxicity induced by kainate
- P47phox plays a critical role in the apoptosis and reactive microgliosis induced by methamphetamine
- Extract of very high frequency wave treated Panax Ginseng Berry induces apoptosis through a mitochondrion-dependent pathway in HepG2 cells
- Anti-inflammatory effects of Crataeva nurvala Buch. Ham. Are mediated via inactivation of ERK but not NF-κB
- Increase of CCR7-dependent dendritic cell migration to lymph node by glucans
- Association between functional KL-VS polymorphism of the KLOTHO gene and aging
- Quantitative determination of DDP-1369, a new drug candidate for anti-parkinson’s disease, in rat plasma by LC-MS/MS, and its application to a pharmacokinetic study
- The Study on Improvement of Clinical Trial Registration and Operation
- Prenatal toll-like receptor-2 activation induces social and cognitive problems in female mice
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- Effect of sarpogrelate on high-fat diet-induced nephropathy
- Modulation of nuclear receptor 4 A by amodiaquine
- Particle design and in vivo evaluation of Eudragit E nanoparticle containing dutasteride
- Chrysin enhanced the therapeutic efficacy of docetaxel in non-small cell lung cancer
- Chemical evaluation of marine sponge extract
- Trp250-hK2 is defective in intracellular trafficking and actives the unfolded protein
- The interaction between Notch-1 and HIF-1α promotes ischemic neuronal death
- Concise Synthetic Approach to Brazilin
- Involvement of mTOR signaling pathways in the neuroprotective effect of Eleutherin against the glutamate-induced hippocampal cell damage, mimicking severe Alzheimer’s disease brain condition
- Zingerone, an active ingredient of ginger, prevents carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats
- Characterization of GT as a drug repressing BACE1 expression in AD animal models
- Licochalcone A from Glycyrrhiza inflate induces cell death through Specificity protein 1 signaling in oral squamous cell carcinoma
- Implication of Jak2/Stat3 signaling pathway in glutathione peroxidase-1-mediated protection in response to cocaine neuroexcitotoxicity
- Efficacy and Safety of Metformin and/or Oral Contraceptives for the Treatment of Polycystic Ovary Syndrome
- Drug Development Targeting Pin1-Catalyzed Conformational Changes in Cancer and Alzheimer’s Disease
- Animal models for preclinical efficacy evaluation of stem cell therapy
- Inhibitors of Transcription Factor NF-κB: Structure-Activity Relationship studies on the Benzimidazole analogs
- Stereoselective total syntheses of (+)-radicamine B and (-)-codonopsinine via chiral anti, syn-oxazine
- Rdiation induced cancer risk assessment via dietary exposure
- IL-32θ inhibits cancer stem cell stemeness and epithelial-mesenchymal transition via STAT3 pathway in colon cancer
- Formulation,characterization and physicochemical evaluation of Melissa officinalis L. leaves tablets
- Ameliorative effect of caffeic acid cyloheylamide on protein kinase IKK-β- dependent immune-mediated early sepsis and liver injury
- The Impact of Pharmacist-Initiated Interventions ImprovingAcute Coronary Syndrome Secondary Prevention
- Target identification of thienopyrimidine derivatives by a chemical biology approach
- A large-scale synthesis of self-assembled DNA nanostructures by rolling circle amplification for delivery of siRNA conjugates
- The prolyl isomerase pin1 interacts with a 90kDa ribosomal protein S6 kinase 2 to enhance TPA-induced cell transformation
- Novel involvement of SPCIP4 through AKT activation in SPC-induced keratin phosphorylation and reorganization in lung cancer cells
- Continuous twin screw granulation and powder rheological characterization of dry granules containing levetiracetam
- Hyaluronic acid-decorated poly(lactic-co-glycolic acid) nanoparticles for delivery systems of docetaxel and tanespimycin
- The role of cell adhesion on drug resistance of cancer cells
- CYP2D6 genetic polymorphism significantly affects pharmacokinetics of Tolterodine
- Development of novel dual-reverse thermosensitive hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial burst effect
- State-of-the art characterization of biopharmaceuticals for QC/QA using advanced mass spectrometry
- Pentedrone, cathinone derivatives induces rewarding effects through dopamine 1 receptor in striatum
- Chiral separation of proton pump inhibitors by capillary zone electrophoresis
- Development of novel humanized therapeutic antibody targeting rheumatoid arthritis
- Chemical constituents from the leaves of Dryopteris erythrosora
- 4-Isopropyl-2,6-bis(1-phenylethyl)aniline 1 originated from Cordyceps bassiana has anti-inflammatory activities in macrophages
- Two new lignans from the Fruits of Schisandra chinesis(Turcz.)Baill
- The influence of a CYP2C9 inhibitor on the pharmacokinetics of Meloxicam
- A friendly health communicator with professional qualification
- Role of moesin in HMGB1-stimulated severe inflammatory responses
- Bioconversion of SB can increase recovery of auditory function in noise induced hearing loss mouse model
- IL-4 mediated suppression of tumor development via activation of STAT6 in melanoma model
- Optimization of culture condition for enhancing the probiotics immunity
- Discovery of active phytochemicals againts non-alcoholic fatty liver disease from Selaginella tamariscina based on dereplication using UPLC-DAD-QTOFMS
- Cordyceps pruinosa Buthanol fraction exhibit anti-inflammatory effect by suppressing of NF-kB activation
- Inhibitory effects of Palmultang on inflammatory mediator production related to suppression of NF-kappaB and MAPK pathways and induction of HO-1 expression in macrophages
- The Impact of Pharmacist-Initiated Interventions ImprovingAcute Coronary Syndrome Secondary Prevention
- Comparative study between different kinds of membrane for in vitro permeation test with Franz' diffusion cells using minoxidil topical solution
- Synthesis and biological activity of imide derivatives
- RQRASA-based peptide analogs as new ligands to inhibit TSLP signaling
- Apatinib in HSA-PEG inhibits VEGF-induced retinal vascular permeability
- Genomic analyses of the three extremely halophilic archaea using next-generation sequencing
- Alzheimer disease and treatment
- Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathway
- Synthesis of novel 4′ α -trifluoromethyl-2′ β -C-methyl-carbodine analogs as anti-hepatitis C virus agents
- Effect of the Conformational Restrictor in Benzamidochromenone derivatives for the inhibition of Interleukin-5
- Identification of inhibition modality of novel inhibitors for pim kinases using a fluorescence polarization assasy
- Effects of cerulein on keratin 8 phosphorylation and reorganization
- Association study of GPC-1 polymorphisms with sporadic CJD
- A pharmacokinetics study of drug-drug interaction between 5-fluorouracil, irinotecan and BST204, a purified ginseng dry extract, after interavenous and intraperitoneal injection administration to rats
- Development of reactive metabolite screening system using human liver microsomes and LC-MS/MS
- Role of PIMT in transcriptional activation mediated by B-catenin
- Structures, biological activities, and CD effects of azaphilones from Penicillium sp. KCB11A109
- Modified delivery of axitinib that are nanohybrid liposomal nanoparticles effects on hypoxic tumor growth
- Preparation of taste-masked solid dispersion containing palonosetron hydrochloride and evaluation of taste-masking efficiency using E-tongue
- The degradation profile and pH stability of Tenofovir Disoproxil
- Lactobacillus OK67 ameliorates collagen-induced arthritis in mice
- A novel series of indole derivatives inhibit hepatitis C virus replication through induction of pro-inflammatory cytokines
- Identification and mechanistic understanding of a novel targeted agent selective to NAPRT1-deficient lung cancer
- Paclitaxel and TNF-related apoptosis-inducing ligand (TRAIL)-loaded albumin nanoparticles for tumor combination therapy
- Application of physiologically based pharmacokinetic (PBPK) modeling in prediction of pediatric pharmacokinetics
- Chromatographic enantiomer separation and determination of chemical and optical purity of α-amino acids and methyl esters as fluorenylmethoxycarbonyl derivatives with fluorescence detection
- Pharmacy Students’ Social Network Service Activities and Perceptions Regarding E-Professionalism in Korea
- Modulatory effect of bakuchicin on CYP1A in human liver microsomes
- Phaseollin inhibits endotoxin-induced inflammation in murine macrophages
- The change of ginsenoside composition of Black ginseng depending on extracting conditions
- Targeting of breast cancer stem cells using hyaluronan-conjugated liposome encapsulating gemcitabine
- Pharmaceutical care service, a crucial sector in national healthcare system
- Anti-cancer effect of (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol on colon cancer cell growth by inhibitor of STAT3 pathway
- Aminopyridinol derivatives inhibit serotonin- and MDA-MB-231 human breast cancer-induced angiogenesis
- Liquid chromatographic determination of creatine, dicyandiamide and dihydrotriazine in dietary supplements
- Persicarin isolated from the Oenanthe javanica protects against diabetes-induced oxidative stress and inflammation in the liver of streptozotocin-induced type 1 diabetic mice
- Promising anti-diabetic potential of capillin and capillinol isolated from Artemisia capillaris
- Molecular modeling & synthesis of 11β-hydroxysteroid dehydrogenase type 1 inhibitor
- Organic anion transporter 3-mediated transport of verproside
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의약학 > 내과학분야 NEW
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- Fractal analysis of mandibular bone structure in individuals with unilateral crossbite
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