Higher Prevalence of Hypertension among Individuals with Restless Legs Syndrome: A Meta-Analysis

• 발행기관: 대한신경정신의학회
• 저자명: In Cheol Hwang Kyoung-Sae Na Yu Jin Lee Seung-Gul Kang
• 간행물 정보: 『Psychiatry Investigation』제15권 제7호, 701~709쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2018.07.31

영문 초록

Objective This study investigated the proposed association between restless legs syndrome (RLS) and the prevalence of hypertension. Methods A meta-analysis was conducted based on searches of the PUBMED, EMBASE, Cochrane Library, and Korean electronic databases. Cohort and cross-sectional studies reporting the incidence of hypertension in individuals with RLS were included. Dichotomous data were pooled to obtain an odds ratio (OR) and 95% confidence interval (CI) for the prevalence of hypertension in individuals with RLS. The main outcome measure of the study was prevalence of hypertension in patients with RLS compared with a control group. Results One cohort study and eight cross-sectional studies were included in the meta-analysis. Individuals with RLS had an increased prevalence of hypertension (all studies: OR=1.13, 95% CI=1.04–1.23; cross-sectional studies: OR=1.12, 95% CI=1.01–1.24). However, in subgroup analyses controlling for cardiovascular risk factors, such as diabetes mellitus and dyslipidemia, the differences in the prevalence of hypertension between RLS and control patients were no longer significant. Conclusion Patients with RLS may have a higher prevalence of hypertension, according to a pooled analysis, but the results remain to be confirmed in well-designed prospective studies.

목차

INTRODUCTION

METHODS

RESULTS

DISCUSSION

키워드

Restless legs syndrome Hypertension Prevalence Meta-analysis