주요 우울 장애 환자의 면역기능에 관한 연구

• 영문명: Immune Function of the Patients with Major Depressive Disorder
• 발행기관: 대한신경정신의학회
• 저자명: 김용희 이재광 박두병
• 간행물 정보: 『신경정신의학』제36권 제3호, 457~465쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1997.05.30

영문 초록

The authors compared 30 depressive patients with 32 normal controls to see the change of immunity in major depressive disorder and study the relationship between altered immunity and variables such as sex, age, and symptom severity. The results of this study were as follows： 1) Percent of suppressor T cell in depressive patients was significantly lower than that of normal controls and IgA concentration of depressive patients was significantly higher than that of normal controls. 2) In the depressive patient group, male patients showed significantly lower number in total lymphocyte, number and percentage of B cell, and IgA concentration than in the female patients. 3) In depressive patient group, a positive correlation was found between percentage in lymphocyte and age and in control group, positive correlations were found among percent of T lymphocyte, number and percentage of helper T cell and age. Negative correlation between IgM and the symptom severity assessed by HDRS was observed in depressive patient group.

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키워드

Major depressive disorder Immune function