종격동 전이를 동반한 역형성 갑상선암의 다학제 치료 경험 1예

• 영문명: A Case of Multimodal Treatment for Anaplastic Thyroid Carcinoma with Mediastinal Metastasis
• 발행기관: 대한두경부종양학회
• 저자명: 조영록(Young Rok Jo) 김정현(Jounghyun Kim) 윤지형(Jihyong Yun) 이혜란(Hye Ran Lee)
• 간행물 정보: 『대한두경부종양학회지』제41권 제2호, 21~25쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2025.11.30

국문 초록

Anaplastic thyroid carcinoma (ATC) is one of the most aggressive and lethal solid tumors, and its therapeutic outcomes remain extremely limited. The main objectives of treatment are to minimize the risk of airway obstruction, control disease burden, and relieve symptoms through a multidisciplinary approach. Surgery is recommended only for localized disease when complete resection is feasible, and morbidity is acceptable. A 62-year-old man presented with a right supraclavicular mass and hoarseness. Imaging revealed a right thyroid tumor with lymph node metastases to the supraclavicular, superior mediastinal, subcarinal, and hilar areas. He underwent total thyroidectomy, bilateral central neck dissection, right modified radical neck dissection, and VATS mediastinal lymph node dissection. Final pathology confirmed a squamous cell carcinoma pattern of anaplastic thyroid carcinoma. Adjuvant radiotherapy and palliative targeted therapy were administered, and he remained stable for 8 months. This case highlights the potential role of surgery in selected ATC patients.

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키워드

Mediastinal involvement Multimodal treatment Surgical management Thyroid anaplastic carcinoma Palliative treatment