학술논문
Age-dependent brain subcortical white and gray matter disruptions in patients with posttraumatic stress disorder
이용수 0
- 영문명
- 발행기관
- 대한해부학회
- 저자명
- Kambiz Kangarlou Samira Raminfard Jayran Zebardast Elham Faghihzadeh Bahman Jalali Kondori
- 간행물 정보
- 『Anatomy and Cell Biology』Vol.58(2), 220~228쪽, 전체 9쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2025.06.30
4,000원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
Posttraumatic stress disorder (PTSD) is a psychiatric condition that can develop after experiencing a traumaticevent, and it is associated with a range of functional and structural brain abnormalities. This study aimed to investigateage-related differences in subcortical gray and white matter in veterans with PTSD. This study recruited 44 patients withPTSD and 48 healthy controls. Participants were divided into two age groups to evaluate structural magnetic resonanceimaging analysis. The results showed that individuals with PTSD had significantly smaller subcortical gray matter volumes,including the bilateral thalamus, hippocampus, amygdala, left pallidum, and right accumbens-area (P<0.05). Diffusion tensorimaging analyses revealed lower fractional anisotropy in several white matter structures, including the anterior limb of theinternal capsule, anterior corona radiata, and cingulum in both hemispheres (P<0.05). Additionally, the mean diffusivitywas higher in the anterior limb of the internal capsule, anterior corona radiata and the right external capsule (P<0.05). Acomparative analysis between two age groups, over 50 and under 50 years old, showed that younger PTSD patients had areduction in volume and abnormality in the corresponding white matter in more regions compared to the control group. These findings suggest that PTSD is associated with significant structural alterations in the brain, which may contribute tothe pathophysiology of the disorder. So, patient age is an effective factor in exposure to traumatic events and an older age iscontinuously associated with a worsening traumatic brain injury outcome.
영문 초록
목차
Introduction
Materials and Methods
Results
Discussion
ORCID
Author Contributions
Conflicts of Interest
Funding
References
해당간행물 수록 논문
- The trochlea for the intermediate tendon of the digastric muscle: a review
- Reliability of Sedillot’s triangle as a potential anatomical landmark for central venous catheter insertion: insights from cadaveric study
- Surgical anatomy of the anterior musculocapsular complex of the hip: a macroscopic and microscopic anatomical reappraisal
- Enhancing anatomy education using anatomical sign language: expanding its expressive capabilities to the upper and lower extremities, face, and brain structures
- Morphological analysis of occipital condyle and superior articular facet of first cervical vertebra and its congruence in a Thai population
- Ossification of bony nerve canals in the human head: a comparison between the endochondral and membranous bones
- Arsenic and vanadium co-exposure induced cerebellar neurotoxicity: aggravates apoptosis, inflammation, oxidative stress, and locomotor deficits in juvenile BALB/c mice
- Liver oval cells in response to HDAC1 inhibitor trichostatin A: immunohistochemical characterization using OV-6 hepatic expression
- Peripheral neuroprotective potential and toxicological profile of fascaplysin in zebrafish models
- Preconditioning enhances neurotrophic factor expression in rat bone marrow mesenchymal stem cells for neuroregenerative applications
- Variant of the coracohumeralis muscle
- A Y-shaped sphenoidal sinus septum: a case report
- Azygos lobe: exploring the bronchial supply and clinical implications
- Concurrent variations of left testicular vessels
- Lard is a simple thermo-responsive and environmentally-friendly filler for vascular perfusion in cadaver surgical training
- Branched ends of Reichert’s cartilage in the ear: a histological study using human near-term fetuses
- Age-dependent brain subcortical white and gray matter disruptions in patients with posttraumatic stress disorder
- Hair follicle stem cell-derived secretome protects astrocytes in an in vitro ischemia/reperfusion model
- A constellation of anatomical variation: middle scalene, wrist extensor, and aortic arch variants share embryological origins in cervical somites
참고문헌
관련논문
의약학 > 의학일반분야 BEST
더보기의약학 > 의학일반분야 NEW
- Factors associated with malnutrition in nursing home residents: A systematic review and meta-analysis of observational studies
- Developing nursing competencies to support healthy aging in the era of super-aged society: A Delphi approach
- Factors influencing self-decision in withholding or withdrawal of life-sustaining treatments among older patients admitted to general hospital: A retrospective case-control study
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!