Radium-223 Dichloride의 외부 방사선량의 평가

• 영문명: The Evaluation of External Radiation Exposure dose rate for Radium-223 Dichloride
• 발행기관: 대한핵의학기술학회
• 저자명: 조성욱(Seong Wook Cho) 윤석환(Seok Hwan Yoon) 승종민(Jong Min Seung) 김태엽(Tae Yub Kim) 임정진(Jeong Jin Im) 김진의(Jin Eui Kim)
• 간행물 정보: 『핵의학기술』Vol.20 No.1, 28~31쪽, 전체 4쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2016.05.30

영문 초록

Purpose ²²³Ra-Dichloride is used for the medicine of castration-resistant prostate cancer (CRPC) and which emits α-ray of 28 Mev that is used for therapy. However ²²³Ra-Dichloride emits β-ray of 3.6% and γ-ray of 1.1%(80,156,270 keV) aside from α-ray in decay. Therefore we would like to evaluate external radiation expose dose rate of γ-ray of ²²³Ra-Dichloride. Materials and Methods We calculated external radiation expose dose rate using γ-constant of ²²³Ra-Dichloride, ⁹⁹ᵐTc based on Health physics(2012). ²²³Ra-Dichloride of 3.5 M㏃ and ⁹⁹ᵐTc-MDP of 740 M㏃ were applied. external radiation expose dose rate 15 times from 1m by survey meter. Results γ-contant of ²²³Ra, ⁹⁹ᵐTc-MDP from 1m distance based on Health physics(2012) is 0.0469, 0.0215. calculated value of external radiation expose dose rate was 16 μ㏜, 34 μ㏜ which activity is ²²³Ra-Dichloride of 3.5 MBq and ⁹⁹ᵐTc-MDP of 740 M㏃ from 1 m . and measured mean value of 1 m was 0.7 μ㏜/h, 18 μ㏜/h. Conclusion γ-constant of ²²³Ra is higher than ⁹⁹ᵐTc based on Health physics(2012). however calculated maximum external radiation expose dose rate of ²²³Ra-Dichloride is lower than ⁹⁹ᵐTc due to actually used quantity of activity of ²²³Ra-Dichloride is small. measured value of ²²³Ra-Dichloride is also lower than ⁹⁹ᵐTc-MDP. Therefore external radiation expose dose rate of γ-ray of ²²³Ra-Dichloride is very low.

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실험 재료 및 방법

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키워드

²²³Ra-Dichloride external radiation expose dose