Morphology of the human aorta and age-related changes: anatomical facts

• 발행기관: 대한해부학회
• 저자명: Pornhatai Komutrattananont Pasuk Mahakkanukrauh Srijit Das
• 간행물 정보: 『Anatomy and Cell Biology』Vol.52(2), 109~114쪽, 전체 6쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2019.06.30

영문 초록

Aorta is the largest artery in the human body. Its starting point is the aortic orifice of the aortic valve and it terminates at the level of the fourth lumbar vertebra. The main function of the aorta is to transport oxygenated blood to supply all the organs and cells. With advancing age, the structure and hence the function show progressive changes. Various changes in the aortic morphology include the luminal diameter of aorta, whole length of the aorta, thickness, the microstructural components also change, and these include collagen, elastin and smooth muscle cells. In addition, the dimensions of all segments of the aorta increase with age in both sexes. Since age is a major risk factor for degenerative change and diseases affecting the aorta, understanding the detailed anatomy of the aorta may provide essential information concerning the age-associated process of the aorta. Knowledge of the morphological changes in the aorta is also important for future clinical therapies pertaining to aortic disease. Additionally, the information regarding the structural changes with age may be applied for age determination. This review describes the overview of the anatomy of the aorta, age related changes in the morphology of the aorta and aortic diseases.

목차

Introduction

The Anatomy of the Aorta

Age-Associated Changes in the Morphology of the Human Aorta

Atherosclerosis

Future Direction

Conclusion

References

키워드

Aorta Thoracic aorta Abdominal aorta Age change