삼차신경통으로 진단된 하치조신경의 절제와 조직변성

• 영문명: HISTOPATHOLOGIC FINDINGS OF THE DEGENERATED INFERIOR ALVEOLAR NERVES RESECTED DUE TO REFRACTORY TRIGEMINAL NEURALGIA
• 발행기관: 대한구강악안면외과학회
• 저자명: 김명래(Myung Rae Kim) 성만호(Man Ho Sung) 구혜수(Hye Soo Koo)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제23권 제4호, 656~667쪽, 전체 12쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 1997.10.30

영문 초록

This is to report the histo-pathologic findings of the degenerated inferior alveolar nerves(IAN) causing uncontrollable neuralgia persisted for over 3 years. The patients had sufferred from frequent attack of unbearable pain along the mandibular branches of the Vth nerve. The pain arised spontaneously 5-10 times a day and lasted for 2-5 minutes. The medications including Tegretol were neither so effective to alleviate the pain level, nor enough to keep free from pain all days. The peripheral neurectomies were preceded by diagnostic nerve block, and partial resection of the IAN in the mandibular canals were approached by sagittal split osteomy of the ramus. The histopathologic findings of the resected IAN were as follows ; 1. Special staining with Luxol Fast Blue (LFB) and Masson Trichrome (MT) disclosed marked degeneration of the axons, decreased in number and fibrosis between the nerve fibers. 2. EM study revealed destruction of myelin continuity surrounding axons, degeneration of Schwann cell and endoneureal sheath, and coarse collagen between the destructed axons. 3. The 3 of 6 patients presented again with recurred pain in 2-3 years after the peripheral neurectomies. Excisional biopsy of the retromolarpterygomandibular softtissues disclosed the collateralization neuropathy beside the long-buccal nerves and their neuromatous findings.

목차

Abstract

I. 서론

II. 연구대상 및 방법

III. 연구결과

IV. 고찰

V. 결론

참고문헌

키워드

Trigeminal neuralgia peripheral neurectomy Nerve degeneration