수술 후 부갑상선기능저하증 환자에서 발생한 우유-알칼리 증후군

• 영문명: Milk-Alkali Syndrome in a Patient with Postoperative Hypoparathyroidism During Long-Term Maintenance of Calcium Supplementation
• 발행기관: 대한내분비외과학회
• 저자명: 김철수 김부경 최영식 박요한 권수경 Cheol Su Kim Bukyung Kim Young Sik Choi Yo-Han Park Su Kyoung Kwon
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』14권2호, 85~88쪽, 전체 4쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2014.06.30

영문 초록

Calcium plays a critical role in neuromuscular excitement and other cellular functions. Therefore, extracellular calcium concentration is maintained within a very narrow range through interaction of calcium regulating hormones such as parathyroid hormone, cal-citonin, and vitamin D. Thus, symptomatic severe hypercalcemia has rarely occurred in a clinical situation, particularly in patients with hypoparathyroidism. In general, a large amount of calcium and vitamin D should be supplied in order to avoid hypocalcemia in hypoparathyroid patients. A 63-year old female patient was admitted suffering from nausea, vomiting, and weakness for two weeks. She had a history of total thyroidectomy and subsequent permanent hypoparathyroidism and long-term calcium and vitamin D supplementation. For over 10 years she had not changed her daily amount of calcium and vitamin D intake. Her initial serum calcium was 17.5 mg/dL, creatinine was 2.57 mg/dL, and total CO2 was 33.1 meq/L. After thorough examination, we concluded that milk-alkali syndrome was the cause of severe hypercalcemia. Therefore, special pay attention should be paid to aged patients on calcium supplementation in situations of increased risk of dehydration and renal insufficiency, even though the usual amount of calcium intake was unchanged for several years.

키워드

부갑상선기능저하증, 우유-알칼리 증후군, 고칼슘혈증, 칼슘,Hypercalcemia, Hypoparathyroidism, Milk-alkali syndrome, Calcium