학술논문
Synthesis of L-sangivamycin and toyocamycin analogues, and their inhibitory activities of Ser/Thr protein kinases
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- Moon Woo Chun Dae Hong Shin Sun Yong Song Yong Hee Lee Chul Hoon Lee Lak Shin Jeong Seung Ki Lee
- 간행물 정보
- 『정기총회 및 학술대회』제47회 정기총회 및 학술대회, 205~205쪽, 전체 1쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 1998.10.31
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- 팔선 양조용수외 세포독성 및 항암활성
- Inhibition of nitric oxide production by polyacetylenes from Angelica gigas in LPS-activated RAW 264.7 cells
- 화장품의 특수성분에 관한 연구(X) -Ion chromatography에 의한 화장품중의 유기산 분석법 -
- Chitin synthase Ⅱ inhibitory activity of ursolic acid, isolated from Crataegus pinnatifida
- Metabolism of myristicin in rat isolated perfused liver
- Determination of terbutaline enantiomers in human plasma by achiral-chiral high performance liquid chromatography
- New sensitive analysis of lovastatin acid by HPLC with UV detection in human volunteers
- An endogenous proleinacious inhibitor for S-adenosyl-L-methionine-dependent transmethylation reactions ; Identification of ACP (acyl-carrier protein) like glycoprotein
- The effect of hypoxic condition on the regulation of CYP4501A1
- Oxazolidinone-cephalosporin quaternary ammonium salts
- Stereoselective synthesis of 1β methylcarbapenem key Intermediate
- Fumonisin-induced activation of Caspase 3 is related to the disrupted sphingolipid metabolism in LLC-PK1 cells
- Studies on safety evaluation of imported cosmetics -Investigation on skin irritancy of cosmetics by human patch testing-
- Effects of zinc chloride on the immunobiological responses of lipopolysaccharide
- Antipiatelet aggregation mechanism of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthalendione
- Comparison of metabolites in rat urine between L-deprenyl and methamphetamine administration by capillary electrophoresis
- Neutrophil이 생성하는 reactive oxygen radical의 생성억제 및 제거활성을 가지는 천연물 검색
- Inhibition of reactive oxygen species-induced genotoxicity by alpinia officinarum and its major flavonoid, Galangin
- 새로운 PDE저해제 CJ-1082의 항 천식 약효
- Studies of signal transduction pathway of the high affinity IgE receptor (Fc£RI) using yeast two-hybrid system
- Lignan components from the flower buds of Magnolia fargesii
- Analysis of sugar alcohols in amino acid infusion by Bio-LC
- Characterization of immunotoxins by capillary electrophoresis and MALDI-TOF mass spectrometry
- Identification of IY81149 and its metabolites in the rat plasma using the on-line HPLC/ESI mass spectrometry
- Determination of cisapride in rat serum samples using microbore HPLC with column-switching
- 참취로부터 수용성 알카로이드 분리
- H-ras와 N-ras가 도입된 Human Breast Epithelial Cell에 Capsaicin이 미치는 영향에 관한 연구
- Inhibition of mouse skin tumor promotion and phorbol ester induced NF-kB activation in cultured HL-60 cells by diarylheptanoids structurally related to curcumin
- Regulation of cyclooxygenase via NF-kB by age and dietary restriction
- Mbdes of Neuronal Injuiy Induced by Transient Focal Cerebral Isdienia in Rats
- Use of recombinant human cytochrome P450 1A2 expressed in Escherichia coli for bacterial mutagenicity assay
- 知母로부터 새로운 norlignan 화합물의 분리 및 hyaluronidase 억제효과
- Ceramide-mediated apoptosis involves modulation of p27kip1 expression and cyclindependent kinase activities
- 5-Aminosalicylic acid의 결장표적성 prodnig의 개발: 5-aminosalicyl-L-cysteine의 합성 및 성상
- Effect of glutathione on anticancer agents-induced apoptosis
- 손바닥선인장의 열메와 줄기의 생리활성 연구(1)
- Cercis chinensis의 잎으로부터 단리한 phenol성 화합물 및 tyrosinase 활성 억제효과
- 들깨잎 polyphenol oxidase의 세포내 분포 및 특성
- 민간약「노루귀」생약학적 연구
- Fermentation of recombinant insulin analogue in Escherichia coli and its purification by affinity chromatography
- Demonstration of cytotoxic T cell response to HBV antigen in putative nonresponder mice.
- Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from the several medicinal plants
- 은행잎 polyphenol oxidase의 세포내 분포 및 효소반응 생성물의 특성
- Pharmacokinetics of indomethacin after intravenous administration to premature infants for prophylactic treatment
- Up-regulation of protein kinase C iso forms protects RAW264.7 macrophages from nitric oxide-induced apoptosis
- Inhibitory activity of apigenin-7-O-D-glucopyranoside from Charaganae root on immediate and late phase asthmatic responses in guinea pigs
- 1-(2-furyl)-3-(sub.(R)-phenyI)propenone 유도체들의 정량적 구조-활성 상관관계 (QSAR)
- Inhibitory effects of bulbocapnine on dopamine biosynthesis in PC12 cells
- 권삼(Polygonum bistorta)의 활성성분 연구
- Defferential expression of ATX according to the metastatic potentials of tumor cells
- The cytotoxicity and topoisomerase I inhibition of Rubus crategifolius extracts
- Cytotoxic constituents of Gymnaster koraiensis
- Toxicity of tetraarsenic hexoxide
- Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum
- 돼지 비장에서 phospholipase A2의 분리 정제 및 억제제 개발
- Protoberberine 계열 화합물이 P815 세포중의 serotonin 생합성 과정에 미치는 영향
- Efficient synthesis of 3-arylisoqumoline-1(2H)-ones and nucleophilic substitution in the reactions of arendiazonium cations with nitrile ion
- Cyclooxygenase-2 저해제의 합성과 그 생물학적 활성
- Synthesis of optically active 7 y-azetidinyl-β-hydroxy-α-amino acid moiety of mugineic acid
- Cytotoxic novel polyacetylenes from the marine sponge Petrosia sp.
- Urinary excretion of dextromethorphan in human
- Self-emulsifying system 을 이용한 난용성 약물의 drug delivery (Ⅳ) indomethacin 의 selfemulsifying drug delivery system
- 항염효과가 기대되는 4-oxo 1,2-benzothiazine 유도체의 합성
- Optimal synthesis conditions of hydrotalcite
- Artemisia feddei의 Inducible Nitric oxide Synthase 억제물질
- Pharmacokinetic and pharmacodynamic evaluation of cyclosporine a as O/W-emulsion formulation
- The effect of skin permeation enhancers on the transdermal delivery of testosterone from a novel soft hydrogel
- Prepration and characterization of tablets containing cefatrizine propylene glycol enteric-microencapsulated or microagglomerated by spray-drying method
- 방사성 활액막 절제술용 Re-188 주석 교질의 제조
- 7-O-p-Fluorobenzoylchrysin의 물성 및 혈당강하효과
- Purification of NO synthase in Staphylococcus aureus
- Purification and gene cloning of a chitinase from Cytophaga sp. HJ
- 오미자로부터 분리된 lignan 화합물의 PAF 길항효과
- Novel ginseng saponin metabolites
- Synthesis and Comparative Molecular Field Analysis (CoMFA) of Antitum or 3-Arylisoquinoline Derivatives
- Receptor-mediated gene delivery to cells of hepatic origin by galactosylated macromolecule-peptide complex
- A triterpene glycoside from leaves of Acanthopanax divaricatus var. albeofructus
- Renal action of BRL 34915, K+ channel opener, in dog
- 3T3-L1 Cell에서 상엽 물 및 에탄올 추출물이 glucose transporter, ACC, FAS gene expression에 미치는 영향
- Onion has more beneficial antithrombotic effect in diabetic rat
- Quantitative Low-Dose assessment of neurotoxin in the brain: Application of PBPK modeling
- Nitric oxide synthase외 만성억제로 유발된 고혈압에서 혈관조직내 adrenaline성 수용체와 angiotensin II 수용체 반응의 변화
- Activation of Fe £ RI inhibits the pyruvate kinase activity by directly interacting through y chain
- Naphthazarin derivatives: synthesis, cytotoxic mechanism and evaluation o f antitumor activity
- New Targets for New Antibiotics
- 모세담관막에는 TBuMA에 선택적인 ATP 의존성 배설 수송계가 존재한다.
- 수종 생약의 murine embryonic hepatocyte BNL-cl.2 cells 보호 효과
- Cytotoxicity and effect on cell cycle of norcepharadion B to cancer cells in vitro
- Detection of DNA bands on electrophoresis using indoine blue and methylorange
- 양강 및 정향으로부터 C0X-2 저해제의 분리
- Flavonoids from the leaves of Caragana chamlagu
- 담도결찰 흰쥐에서 마디풀(Polygonum aviculare L.)의 간섬유화 억제효과
- 단백분해성 펜타펩타이드인 Pz-peptide의 간내 이행 기전
- Effect of pore formers on the controlled release of antibiotics from a polymeric device
- 수술 후 장페색의 병태 상황에서 위장관 운동 기능을 측정할 수 있는 새로운 실험게의 개발
- Carrier mediated transport of YH-1885 across caco-2 cell monolayers
- Changes of GABA receptor binding and GABA receptor subunit mRNA level in nitric oxide synthase inhibitor-infused rat brain
- Kosamol A, a novel prenylated flavonoid, arrests the cell cycle at G0/Gl stage
- 새로운 염증성 대장염 치료제인 DA-6034의 acetic acid-유발성 대장염에서 치료효과
- 온도가역성 및 생체부착성 액상좌계의 개발
- Metabolism and excretion of fenfluramine in human urine
- Classification of Ginseng radix using near infrared reflectance spectroscopy
- 진피(秦皮)의 Nitric oxide 생성 억제물질
- Characterization of hapten-specific T cell functions in response to altered antigenic ligands
- Asymmetric Michael reaction using C2 symmetric chiral malonamide
- Dehydroevodiamine(DHED)의 혈장, 담즙 및 요중 정량법
- YH1885의 결정 구조
- Dehydroevodiamine(DHED)의 생체내 동태
- Optimization study on the formulation of roxithromycin dispersible tablet using experimental design
- Procollagen N-terminal peptide 확인을 위한 표준물질 및 항체생산에 관한 연구
- β-carotene 함유 alginate beads의 용출에 미치는 계면활성제의 영향
- Poly(ortho esters)를 이용한 Nifedipine의 반고형 이식제제의 제조 및 평가에 관한 연구
- The effect of various penetration enhancers on the percutaneous absorption of prostaglandin E1
- 약물의 담즙배설을 예측할 수 있는 샌드위치형 간세포 배양계의 개발
- A new route to the synthesis of cephem derivatives
- Synthesis and characterization of immunotoxins containing deglycosylated ricin A-chain
- Optical resolution of [3.2.0] bicyclic amines with L-tartaric acid
- 2,5-Dihydro-4-methyl-2-phenyl-1,5-pyrido(2,3-c)thiazepine-3-carboxylic acid ester의 합성
- 1-azaanthraquinone-3-carboxamide 유도체의 합성 및 세포독성
- The syntheses and biological evaluations of 5-pyrrolocarbonyl-2-(pyridylmethylsulfinyl)benzimidazole derivatives as gastric antisecretory agent
- Inhibitory effect of nitric oxide on the cyplal gene expression
- 보양제에 속하는 생약의 항산화 효과
- Synthesis of camptothecin analogues having Antitum or Activity: Modification of E ring or both E and A or B ring
- Simultaneous gas chromatography of organic acids and amino acids in Baekgangjam and Dongchunghacho
- 저산소 및 산소재도입시 저산소 모델에 따른 약물대사 효소계의 변동
- 의약품의 품질평가에 관한 연구 (I) -CE를 이용한 효소제의약품의 품질연구(염화리소짐 제제) -
- 모델항원인 Ovalbumin을 함유하는 생분해성 미립자의 제조 및 특성
- Antioxidant effect of astragalic radix
- 흰쥐에서 selegiline 및 Ginkgo biloba extract(EGb 761)외 병용처치시 중추신경계에서의 상호작용
- Bradykinin에 의한 혈관반응에 있어 Enalapril 과 Ginkgo biloba extract(EGb 761)의 영향
- 고탄수화물식이 섭취 마우스에서 acarbose의 glycosidase, glucose transporter 및 leptin 유전자 발현에 미치는 영향
- Expression and functional analysis of tissue inhibitor of metalloproteinasel (TIMP1) wild-type and mutants expressed by baculovirus/insect cell system
- Determination of paeonol and paeoniflorin in moutan root-bark by capillary electrophoresis(CE)
- Activators and inhibitors of thrombin from mushrooms
- Pharmacokinetics of losartan and its metabolite, exp3174, after intravenous and oral administration of losartan to rats with streptozotocin-induced diabetes mellitus
- Streptozotocin 유발 세포독성에 대한 상엽의 보호활성
- Annocherin A, B, C and corossolin, three novel and a known cytotoxic annonaceous acetogenins from the seeds o f Annona cherimolia.
- 다양한 그람음성균에 작용하는 lipopolysaccaride-outer membrane protein microsome vaccine외 독성 및 유효성 확인
- 기체크로마토그래피법을 이용한 혈중에서의 very long chain fatty acids (VLCFA)의 정량분석에 관한 연구
- 새로운 modified nucleosides의 합성
- Synthetic approaches of natural benzo[c]phenanthridine alkaloids
- Nitric oxide and hypoxia effect on TCDD induced EROD activity
- Effect of biphenyl dimethyl dicarboxylate (DDB) on drug metabolizing enzyme, CYP450 in rat liver
- 나도냉이 (Barbarea orthocerus LED)의 tyrosinase 저해활성 물질
- 참취로부터 조직인자저해제 분리
- A suppressive component on phagocytic activity of peritoneal macrophage in Aurantii immaturi pericarpium
- Phagocytic activity of lithospermi radix on peritoneal macrophage in mice
- 백지로부터 항염작용이 있는 물질의 분리
- 1d와 유사한 새로운 HLH유전자의 클로닝 및 특성연구
- 채소류외 dopamine β-hydroxylase 및 monoamine oxidase 저해작용 검색
- Phenolic compounds from the leaves of Clerodendron trichotomum
- Benzylalcoholglycoside from Gastrodia elata
- Quantitative analysis of taurine using near infrared spectrometry (NIRS)
- Development and optimization of TTS containing clebopride
- Design and synthesis of chiral cycloruthenated complexes and their properties
- Aminophylline 복용시 물의 양어 theophyllineCTP)의 체내 동태에 미치는 영향
- Measurement of protein concentration using an Eosin Y dye
- Effects of chlorhexidine on structural parameters of total lipid liposomes extracted from Anaerobic Bacterial Membranes
- Multidrug-resistance reversal activities of verapamil, quinidine, cyclosporin A, nicardipine and tamoxifen
- 차전자의 활성성분 연구
- Effects of polycyclic hydrocarbons on human cytochrome P4501A2 gene (CYP1A2) promoter Activity
- 다시마의 체중증가 억제작용
- Anti-allergic action of resveratrol and related hydroxystilbenes
- 메실산 가백세이트 유도체로부터 항전이효과
- Studies on the Cell Cycle Modulators in Human Breast Cancer Cells
- 퀴놀론 항균제의 현황과 전망
- Drug Designs Based on Insect Defense Molecules
- β-Cyclodextrin 과 chitosan이 Flurbiprofen의 피부투과에 미치는 영향
- Selective cytotoxicities of novel platinum(Ⅱ) complex {[Pt(Ⅱ)(cis-DACH)(DCE)]2NO3} on human ovary cancer cell-lines and normal kidney cells
- Solution Structure of an Antimicrobial Peptide Gaegurin 4
- Structures of proteins which regulate actions of transcription factors
- Production of antibody against 20(S)-protopanaxatiol and triol group saponins of Panax ginseng C.A.Meyer
- 팔선 양조용수의 세포독성 및 항암활성
- The effect of rm IL-18 on the murine peritoneal macrophage
- Antibacterial activity of antimycotic miconazole against methicillin-resistant Staphylococcus aureus
- 구내 염증치료용 구강점막 부착 패취제 개발
- 조구등으로부터 분리된 phospholipase Cy1 저해 활성 triterpene ester
- Benchmark Dose를 이용한 다이옥신의 비발암영향평가
- Purification of protein methylase Ⅱ in Helicobacter pylori
- Lignans from Sorbaria sorbifolia var. stellipila
- TetR-mediated transcriptional activation system in animal virus
- 사철쑥과 그늘쑥의 다당체 분획 연구
- 감초의 β-glucuronidase 저해작용과 간장보호효과
- Anti-inflammatory effects of α-viniferin and epiafzelechin
- Nucleotide sequence of acetaldehyde dehydrogenase gene from Achromobacter xylosoxidans KF701
- Heterologous expression, purification and biochemical characterization of chl D gene involved in 2-deoxy-D-rhamnose biosynthesis from Streptomyces antibioticus Tu 99
- Inhibition of the telomerase activity and catalytic subunit in human breast cancer cells by retionoids in vitro
- Oxytocin의 혈액-뇌관문 투과성과 약물동력학
- The pharmaco-constituents of Korean cultivated Rhubarb Rhizomes (V)
- 야생인삼(人蔘)의 부견
- Araliaceae를 포함한 삼십여종 생약의 소염활성 연구
- Study on anti-OHYUL activity of Rhubarb Ⅱ. Anti-allergic effects of stilbene components from Korean cultivated Rhubarb Rhizomes
- 담자균류로부터 prolyl endopeptidase 및 acetylcholine esterase inhibitor의 탐색
- Regulation of pulmonary reactive oxygen species generation by age and dietary restriction
- 조개나물 전초의 화학성분(Ⅱ)
- Effects of naturally-occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structural-activity relationships
- The characterization and immune response of microglia on Friend virus infection
- Inhibitory activity of 7-oxo-8(14), 15-pimaradiene-19-oic acid from Araliae cordatae root on immediate and late phase asthmatic responses in guinea pigs
- Tungsten-188/Rhenium-188 발생기의 정도관리
- 5-Fluorouracil의 Prodmgs: N-Acyl-2-(5-fluorouracil-1-yl)-D,L-glycine의 합성 및 성상
- 천연물로부터 알코올 탈수소효소, 알데하이드 탈수소효소 활성 저해제 선별
- A New Sesquiterpene from Tussilago farfara
- Naphthalene-2,3-dialdehyde as precolumn labeling reagent for sphingoid bases by reversed-phase liquid chromatography with fluorescent detection
- Physiological concentrations of Pi have an inhibitory effect on the phosphotyrosyl phosphatase activity of plasma alkaline phosphatase
- Anti-allergic action of tanshinone and related derivatives
- 대파중의 벼생장 촉진물질
- Effects of Propolis on Wound healing in Rats
- Production and characterization of monoclonal antibody against Mud protein; its application for determination of the effect of retinoic acid-deficiency on the expression of Mucl protein from hamster tracheal surface epithelial (HTSE) cells
- Induction of apoptosis and endogenous changes of sphingolipid metabolites by FTY-720 treatment in LLC-PK1 cells
- Enalapril과 그 유도체들의 3차원 형태구조에 대한 분자동력학적 모델링 연구
- 나프록센을 함유하는 페취의 제조 및 약물방출과 피부투과
- Melatonin의 토끼 위 장관 흡수 연구
- Tumor-site dependent differential modulation of systemic immunity in RENCA bearing mice
- 형광분석법에 의한 poloxamer 407의 상전이 연구
- New synthetic method for the synthesis of 4,5-disubstituted-pyrrolidinone by palladium catalyzed dicarbonylation from amino acid
- Identification of major metabolite of new platinum (Ⅱ) complexes, KHPC-002 and KHPC-006 in Rats.
- Improvement of dissolution rate of poorly water soluble drug using self-microemulsifying drug delivery system
- Dehydroevodiamine(DHED)의 혈구분배 및 혈장단백결합률
- Synthesis and antimicrobial activity of new cephalosporin having a heterocyclic-pyrrolidinylthio moiety at the C-3 position
- Regulated albumin release from biodegradable hydrogels composed of glycidyl methacrylate dextran and poly(ethylene glycol) macromer
- Detection of cytosolic 100 kDa phospholipase A2 activity in cytosol of bovine brain
- Antiplatelet aggregation mechanisms of green tea catechins and (-)-epigallocatechin gallate
- 새로운 kojic acid 유도체의 합성과 tyrosinase 저해효과
- Syntheses of thiocarbamates, carboxamides, thioamides and cyclic thiocarbamates and their antiviral activities
- 국산 propolis에서의 tectochrysin의 확인 및 정량
- p-Quinone 유도체에 의한 Enoxacin의 정량
- Monoamine oxidase inhibitors from Basidiomycete sp. 8082
- Total synthesis of (± )-homoepibatidine analogues
- 오수유의 안지오텐신 Ⅱ 수용체 결합 저해활성
- Felodipine microsphares의 생체 이용율에 관한 연구
- Preparation of 5-pyrrolyl-6-halo-2-(pyridylmethyl-sulfinyl)benziinidazole derivatives as antiulcer agents
- Synthesis of new monoterpenenoid as potential antitumor agents
- A new method for direct conversion of allyl ethers into allyl carbamates using chlorosulfonyl Isocyanate
- 크라이신의 살리실 유도체에 관한 분석학적 연구
- Antioxidative effect of Rheum undulatum
- Inhibition of platelet aggregation and phosphoinositides breakdown by 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-l,4-naphthalendione in human platelets
- Inhibitory effects of some plants extracts on HIV-1 and its essential enzymes
- 산앵도나무(Vaccinium Koreanum)잎 성분의 분리 및 화학구조
- Comparative neuroprotective activities of KC-508 and KC-497, glycine site antagonists with MK-801 in a rat model of permanent focal ischemia
- Hematological changes in the hypertensive rats induced by lead intoxication
- Low flow hypoxia model에서 Vitamin C의 용량에 따른 효과
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