경주시에서 발생한 세균성이질 확진자에 대한 유행기전 분석

• 영문명: Analysis of Transmission Mode of Confirmed Shigellosis in Gyeongju, Korea
• 발행기관: 한국역학회
• 저자명: 정철(Cheoll Jung) 임현술(Hyun-Sul Lim) 하경임(Gyoung Yim Ha) 김희수(Hee Su Kim)
• 간행물 정보: 『한국역학회지』한국역학회지 제26권 제1호, 1~16쪽, 전체 16쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2004.06.01

영문 초록

Purpose This study was earned out to investigate the sources of infection and modes of transmission of an 107 (54 males, 53 females) confirmed shigellosis in Gyeongju from Sept 24 to Oct 24, 1998 Methods We reviewed hospital records of all confirmed shigellosis Thirty-two stains of Shigella sonnet isolated were analyzed in order to trace the source of infections by plasmid profile, antimicrobial drug resistance pattern, biotyping and pulsed-field gel electrophoresis (PFGE) Results The first source of Infection was estimated to be contaminated underground water and simple piped water caused by leakage from the cess pool Antimicrobial drug resistance pattern showed that all strains were multi-resistant All Isolates had the same XbaI and SfiI PFGE patterns, indicating the epidemiological relationship of the outbreaks strains in this area The major characteristics of diarrhea were watery (84.2%) in nature The clinical symptoms among the diarrheal cases included abdominal pain (86.1%), fever (83.2%), headache (78.2%), chill (45.5%) and tenesmus (41.6%) Six cases were asymptomatic From initial manifestation to admission were 6.2±1 .6 (median 6) days, so It could be transmitted to others in this infective period Duration of admission were 5.5±2.4 (median 6) days We can find familial mean secondary attack rate were 38.5% Conclusion It's transmission to other areas were certified by contaminated water and contact with shigellosis, and unknown cases were estimated to be transmitted by contacts with inapparent infection By plasmid profile and PFGE, the epidemiological relationship of the outbreaks Strains in this area seemed to be the same micro-organisms.

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Abstract