코로나-19 바이러스 감염 증상 : 성인 환자의 정맥주사 및 안전성 평가 연구

코로나-19 바이러스

Yeming Wang , Jianping Zhao , Zhenshun Cheng , Shouzhi Fu , Ke Wang , Fei Zhou , Dingyu Zhang , Ronghui Du , Yi Hu , Ling Gao , Yang Jin , Guangwei Luo , Qiaofa Lu , Guanhua Du , Yang Lu , Guohui Fan , Yi Zhang 지음

아진 2020년 06월 25일 출간

작품소개

책소개

Coronavirus disease 2019 (COVID-19), caused by a novel corinavirus (later named SARS-CoV-2 virus), was fistly reported in Wuhan, Hubei Province, China towards the end of 2019. Large-scale spread within China and internationally led the World Health Organization to declare a Public Health Emergency of International Concern on 30th January 2020. The clinical manifestations of COVID-19 virus infection include asymptomatic infection, mild upper respiratory symptoms, severe viral pneumonia with respiratory failure, and even death. There are no antivirals of proven clinical efficacy in coronavirus infections. Remdesivir (GS-5734), a nucleoside analogue, has inhibitory effects on animal and human highly pathogenic coronaviruses, including MERS-CoV and SARS-CoV, in in vitro and in vivo experiments. It is also inhibitory against the COVID-19 virus in vitro. The aim of this study is to assess the efficacy and safety of remdesivir in adult patients with severe COVID-19.

목차

제 1편 코로나바이러스 정의

1. 코로나바이러스감염증-19(Covid-19) 정보 7
2. 코로나바이러스 분류 및 특성 9
3. 코로나바이러스 전자현미경 형태 11
4. 코로나바이러스 구조 (Covid-19 Organization) 13
5. 코로나19: 환경에 지속적인 영향을 미칠까? 19
6. 치료법(Therapeutical Method) 22



제 2편 연구논문
Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: study protocol for a
phase 3 randomized, double-blind, placebo-controlled, multicentre trial


1. Introduction 23
2. Methods: participants, interventions, and outcomes 25
3. Interventions 25
4. Data collection and management 27
5. Statistical methods 29
6. Discussion 31
7. References 33

작가정보

저자(글) Yeming Wang

저자(글) Jianping Zhao

저자(글) Zhenshun Cheng

저자(글) Shouzhi Fu

저자(글) Ke Wang

저자(글) Fei Zhou

저자(글) Dingyu Zhang

저자(글) Ronghui Du

저자(글) Yi Hu

저자(글) Ling Gao

저자(글) Yang Jin

저자(글) Guangwei Luo

저자(글) Qiaofa Lu

저자(글) Guanhua Du

저자(글) Yang Lu

저자(글) Guohui Fan

저자(글) Yi Zhang