두경부 혈관종 진단시 99mTc-RBC Scan and SPECT 검사의 유용성

• 영문명: Usefulness of 99mTc-labeled RBC Scan and SPECT in the Diagnosis of Head and Neck Hemangiomas
• 발행기관: 대한핵의학기술학회
• 저자명: 오신현(Shin Hyun Oh) 노동욱(Dong Wook Roh) 안샤론(Sha Ron Ahn) 박훈희(Hoon-Hee Park) 이승재(Seung Jae Lee) 강천구(Chun Goo Kang) 김재삼(Jae Sam Kim) 이창호(Chang Ho Lee)
• 간행물 정보: 『핵의학기술』Vol.12 No.1, 39~43쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2008.05.30

영문 초록

Purpose: There are various methods to diagnose hemangioma, such as ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine. However, by development of SPECT imaging, the blood-pool scan using ⁹⁹ᵐTc-labeled red blood cell has been used, because it was non-invasive and the most economical method. Therefore, in this study, we proposed that the usefulness of ⁹⁹ᵐTc-RBC scan and SPECT of the head and neck to diagnose unlocated hemangiomas. Materials and Methods: ⁹⁹ᵐTc-RBC scan and SPECT was performed on 6 patients with doubtful hemangioma (4 person, head; 1 person, neck; 1 person, another). We labeled radiopharmaceutical using modified in vivo method and then, centrifuged it to remove plasma. After a bolus injection of tracer, dynamic perfusion flow images were acquired. Then, anterior, posterior, both lateral static blood-pool images were obtained as early and 4 hours delayed. SPECT was progressed 64 projections per 30 seconds. Each image was interpreted by physicians, Nuclear medicine specialist, and technologist blinded to patient’s data. Results: In 5 patients of all the radioactivity of doubtful site didn’t change in flow images, but, in blood-pool, delayed and SPECT images, it was increased. So, it was a typical hemangioma finding. The size of lesion was over 2 cm, and it could discriminate as comparing to the delayed and SPECT imaging. On the other hand, in 1 patient, the radioactivity was increased in blood-pool images, but, not in delayed and SPECT images, so, it was proved no hemangioma. Conclusion: Using ⁹⁹ᵐTc-RBC Scan and SPECT, we could diagnose the hemangiomas in head and neck, as well as, liver, more non-invasive, economical, and easy. Therefore, it considered that ⁹⁹ᵐTc-RBC scan and SPECT would offer more useful information for diagnosis of hemangioma, rather than otherimaging such as US, CT, MRI.

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키워드

Hemangioma Head and Neck ⁹⁹ᵐTc-labeled RBC SPECT