DNA Damage Protection and Anti-inflammatory Activity of Different Solvent Fractions from Aruncus dioicus var. kamtschaticus

• 발행기관: 한국자원식물학회
• 저자명: Qin Zhang Hye-Young Kim
• 간행물 정보: 『한국자원식물학회지』제27권 제6호, 714~719쪽, 전체 6쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2014.12.30

영문 초록

This study investigated DNA damage protection and anti-inflammatory activity of different solvent fractions from Aruncus dioicus var. kamtschaticus (A. dioicus) aerial parts water extract. As for DNA damage protection, distilled water (H 2 O) fraction displayed the most powerful protection for DNA damage at a concentration of 1 ㎎/㎖. As for anti-inflammatory activity, dichloromethane (CH 2 Cl 2 ) fraction exhibited the highest NO inhibition activity, ranging from 61% to 19% (10-40 ㎍/㎖). Furthermore, the levels of pro-inflammatory cytokines mRNA expressions and intracellular reactive oxygen species (ROS) were employed to verify the anti-inflammatory activity of the CH 2 Cl 2 fraction on further researches. It could be concluded that A. dioicus had a significantly effect of DNA damage protection and anti-inflammatory activity which also as an essential edible vegetable and medicinal species.

목차

Introduction

Materials and Methods

Results and Discussion

References

키워드

Aruncus dioicus var. kamtschaticus DNA damage Reactive oxygen species Anti-inflammation