Topical and Oral Voriconazole in the Treatment of Fungal Keratitis

• 발행기관: 대한안과학회
• 저자명: Sang Joon Lee Jung Joo Lee Shin Dong Kim
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.23 No.1, 45~48쪽, 전체 4쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2009.03.30

영문 초록

We describe two patients with fungal keratitis refractory to standard antifungal therapy whose conditions were managed with voriconazole. The first case is a patient with endophthalmitis and corneal ulcer due to Candida parapsilosis after receiving a corneal transplant. The patient was treated with amphotericin but showed no signs of improvement. Topical voriconazole, oral voriconazole, and intravitreal voriconazole yielded signs of improvement. The second case is a 63-year-old male who underwent a month of empiric treatment with 0.2% topical amphotericin for fungal keratitis but showed no signs of improvement. Treatment was then provided with 1% voriconazole. Both cases showed effective treatment with voriconazole. Voriconazole may be considered as a new method to treat fungal keratitis refractory to standard antifungal therapy.

목차

Case 1

Case 2

Discussion

References

키워드

Fungus Keratitis Voriconazole