Clinical significance of sonographic soft markers: A review

• 발행기관: 대한의학유전학회
• 저자명: Mi Sun Kim Sukho Kang Hee Young Cho
• 간행물 정보: 『대한의학유전학회지』제15권 제1호, 1~7쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2018.06.30

영문 초록

Sonographic findings with little or no pathological significance, known as soft markers, are often found in aneuploidy fetuses. After normal screening for the aneuploidy in first trimester, there are no uniform recommendations regarding when to disregard or put on clinical significance in isolated soft markers. Associations between some soft markers and adverse pregnancy outcomes including intrauterine fetal death, preterm birth, fetal growth restriction, and congenital infection have been reported in euploidy fetuses. The present article aims to review recent literatures about the clinical significance of soft markers after normal first trimester combined screening or noninvasive prenatal testing, and propose a simple clinical summary for management of specific soft markers in pregnancies.

목차

Introduction

Ventriculomegaly

Choroid plexus cyst

Absent or hypoplastic nasal bone

Thickened nuchal fold

Intracardiac echogenic focus

Echogenic bowel

Shortened humerus length and femur length

Fetal pyelectasis

Single umbilical artery

Conclusion

키워드

Aneuploidy Ultrasonography