국소적 신경차단제의 초기 효과에 대한 전기생리학적 연구

• 영문명: Electrophysiological study on the early effect of peripheral neurolytic agents in the rats
• 발행기관: 대한구강악안면외과학회
• 저자명: 강신익(Shin lk Kang) 백운봉(Un Bong Paik) 최병은(Byung Eun Choi) 이희원(Hee Won Lee) 이희철(Hee Chul Lee) 현재만(Jae Man Hyun)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제19권 제1호, 55~62쪽, 전체 8쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 1993.01.30

영문 초록

Rat inferior alveolar nerves were indentified and perfused with glycerol, ethanol, streptomycin/lidocaine mixture and normal saline, using 4 rats in each group. One hour after the operation, electromyograthic recordings were done at the anterior belly of digastric muscle with stimulation of the 1st molar tooth. The following results were found. 1. The threshold intensities to evoke digastric EMG in the streptomycin/lidocaine and saline groups were not significantly different form the control group. 2. The threshold intensity of ethanol group was 5 to 12 times higher, and that of glycerol group was 2 to 2.5 times higher than the control group. 3. There were much individual variations in each experimental animal. 4. Amplitude of digastric EMG was increased following the increase of stimulating intensity. Relationship between amplitude and intensity was linear when the intensity was transformed to the square root. 5. It was suggested that the statistical value of amplitude divided by the square root of the stimulating intensity is representative of the effect of the treated agents. 6. In the group of ethanol, the estatistical value of A/sqI was significantly lower than the control group. In the glycerol group, A/sqI value was lower than the control group but not significant statistically.

목차

Abstract

I. 서론

II. 연구방법

III. 연구성적

IV. 고찰

V. 결론

참고문헌

키워드

Trigeminal neuralgia Glycerol Jaw Opening Reflex