유리체절제술 및 실리콘기름 충전눈에서 트리암시놀론의 유리체강내 주사

• 영문명: Intravitreal Injection of Triamcinolone Acetonide in Vitrectomy with Silicone Oil Placement
• 발행기관: 대한안과학회
• 저자명: 변익수 이지은 엄부섭,Ik Soo Byon, M.D., Ji Eun Lee, M.D., Boo Sup Oum, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number8, 1298~1305쪽, 전체 8쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2006.08.31

영문 초록

Purpose: To evaluate safety and efficacy of intravitreal triamcinolone acetonide (TA) injection at the end of pars plana vitrectomy with silicone oil tamponade. Methods: Eyes which underwent pars plana vitrectomy with silicone oil placement were enrolled. They were followed up for at least 6 months. GroupⅠ (twenty-three consecutive eyes) received an intravitreal injection of 4 mg TA at the end of the surgery, whereas GroupⅡ (twenty-six eyes) did not. Results: Postoperative vision improved by 2 lines or more in 9 eyes (39.1%) of GroupⅠ and 9 eyes (34.6%) of GroupⅡ. The posterior pole was attached in all of GroupⅠ(100.0%) and twenty-four eyes (92.3%) of GroupⅡ (P=0.17). The postoperative BCVA was 5/200 or better in fifteen eyes (65.2%) of GroupⅠand fourteen eyes (53.8%) of GroupⅡ (P=0.51). Eight eyes (34.8%) in GroupⅠ and six eyes (23.1%) in GroupⅡ had an intraocular pressure higher than 21 mmHg (P=0.36). All of them were controlled with medications. Two eyes in GroupⅡ required an additional operation due to recurrence of tractional retinal detachment from the fibrous membrane. Visually significant ocular complications related with TA injections were not noted. Conclusions: The intravitreal injection of TA into silicone-filled vitrectomized eyes seems safe and efficient. But, a prospective study is necessary to demonstrate the long-term safety and efficacy.

키워드

Silicone oil, Triamcinolone acetonide, Vitrectomy