품질 보증을 위한 멸균법이 목단피의 패오놀 함량에 미치는 영향

• 영문명: Effects of Sterilization for Quality Control on the Content of Paeonol in Moutan Radicies Bark
• 발행기관: 대한약학회
• 저자명: 이용수(Yong Soo Lee) 신운섭(Woon-Seob Shin) 조소연(So Yean Cho) 제금련(Keum-Ryon Ze) 이효민(Hyo Min Lee) 정춘식(Choon Sik Jeong)
• 간행물 정보: 『약학회지』제49권 제2호 (2005년), 180~184쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.04.30

영문 초록

The purpose of this study was to develop the best methods to sterilize Moutan Root Bark which is frequently used as a herbal medicine, and known to have high susceptibility to microbial contamination. We used dry heat, gamma irradiation and alcohol gas treatment for sterilization, and evaluated these methods in terms of the followings; I) the efficacy of sterilization, and ii) the chemical alteration of a major component of the harbal medicines. Treatment with dry heat effectively got rid of contaminated microorganisms, and did not significantly alter the content of paeonol. However it seriously changed the color and morphology which are an essential criterion to estimate a measure of quality of medicinal herbs. Treatment with gamma irradiation showed a strong sterilizing effect, and no alteration of the content of paeonol, color and morphology. Alcohol gas treatment resulted in similar effects as those in gamma irradiation. Collectively, these results suggest that appropriate sterilizing methods to guarantee the microbial quality of this herbal medicine may be those using gamma irradiation or alcohol gas.

키워드

Moutan Root Bark sterilizing methods dry heat gamma irradiation alcohol gas paenol