Screening of Plants with Inhibitory Activity on Cellular Senescence

• 발행기관: 한국자원식물학회
• 저자명: Seung-Eun Lee Jae-Ryong Kim Hyung-Jun Noh Geum-Sook Kim Jeong-Hoon Lee Jehun Choi Dae-Young Lee Seung-Yu Kim
• 간행물 정보: 『한국자원식물학회지』제27권 제6호, 601~609쪽, 전체 9쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2014.12.30

영문 초록

In this study, the effect of plant extract on the senescence action and cell survival rate in two types of cells, in which aging was derived by adriamycin, was analyzed to find the materials for suppressing cell senescence from natural resources. The results are as follows. For human umbilical vein endothelial cells (HUVECs), the fruit of Physalis angulata L. and the aerial part of Synurus deltoides (Aiton) Nakai showed excellent cell-senescence inhibition activities in a treatment concentration-dependent manner, demonstrating the high possibility for utilization as a material for prevention and treatment for vascular diseases. The water extract from the root of Polygonatum odoratum var. pluriflorum for variegatum Y. N. Lee showed potent cell-senescence inhibitory effect for human dermal fibroblasts (HDFs). Thus it is considered that the additional study on the plant needs for elucidating the possible utilization as material for skin health improvement.

목차

Introduction

Materials and Methods

Results and Discussion

Acknowledgment

References

키워드

Cellular senescence HDF HUVEC SA-β-gal