Antibiotics - Therapeutic Spectrum and Limitations

Amal Kumar Dhara , Amit Kumar Nayak , Debprasad Chattopadhyay 지음

Elsevier 2023년 07월 01일 출간

작품소개

책소개

Antibiotics: Therapeutic Spectrum and Limitations provides up-to-date information on managing microbial infections, the development and types of antibiotics, the rationale for utilizing antibiotics, toxicity considerations, and the control of antibiotic resistance in one single resource. This book also aims to provide comprehensive insights and current trends on antibiotic therapies to treat microbial infections, their mechanisms of action, and the role of modern drug delivery in improving their efficacy. Written by leading experts from around the globe, the chapters in the book covers important aspects of microbial infections including hospital acquired infections and community acquired infections and adult sepsis, examines the various types of antibiotics with different mechanisms and therapeutic uses, the global challenge of antibiotic resistance, and clinical trials, regulatory considerations, and market overview of antibiotics. Furthermore, the chapters include updated literature reviews of the relevant key topics, high-quality illustrations, chemical structures, flowcharts, and well-organized tables, all of which enable better understanding by the readers.Provides in-depth and updated information and analyses on microbial infections, antibiotics and therapeutics, the consequences of antibiotic resistance, and the role of modern drug delivery in improving efficacyDiscusses different types of antibiotics and their mechanisms as well as traditional medicine, herbal drugs, and postbiotics in the treatment and prevention of microbial infections and management of antibiotic resistanceContributed by global leaders and experts from academia, industry, research institutes, and regulatory agencies

목차

Section I: Introduction 1. Introduction to antibiotic therapy Section II: Microbial infection and antibiotics development 2. Bacterial infection: Types and pathophysiology 3. Antibiotics – Past, Present & Possibilities 4. Challenges in the development of antibiotics Section III: Antibiotics and therapeutics 5. Beta lactum antibiotics 6. Aminoglycoside antibiotics 7. Broad Spectrum Antibiotics (Chloramphenicol and Tetracycline) 8. Macrolide antibiotics 9. Lincosamide and glycopeptide antibiotics 10. Antimicrobial Lipopeptides: Multifaceted Designs to Curb Antimicrobial Resistance 11. Antifungal Compounds: With Special Emphasis on Echinocandins, Polyenes, Heterocyclic Benzofurans 12. Antibiotics in the management of tuberculosis and cancer Section IV: Toxicity and Antibiotic resistance 13. Toxicity consideration of antibiotics 14. Rational use of antibiotics- save antibiotics for future generations 15. Combined use of antibiotics 16. Antibiotic resistance – a global crisis 17. Traditional Medicine in the Management of Microbial Infection as Antimicrobials: Pros and Cons Section V: Others 18. Quinolones as antimicrobial and anti-resistance agents 19. Herbal drugs as antibiotics 20. Paediatric and geriatric uses of antibiotics 21. Role of antibiotics in hospital acquired infections and community acquired infections 22. Adult sepsis as an emerging hospital acquired infection: challenges and solutions 23. Probiotics: A solution to the prevention of antimicrobial resistance 24. Role of modern drug delivery in antibiotic therapy 25. Antibiotic residues in food 26. Clinical trials, regulatory considerations and market overview of antibiotics

출판사 서평

작가정보

저자(글) Amal Kumar Dhara

저자(글) Amit Kumar Nayak

저자(글) Debprasad Chattopadhyay