Managing the Drug Discovery Process

Susan Miller , Walter Moos , Barbara Munk , Stephen Munk , Charles Hart 지음

Elsevier 2023년 03월 22일 출간 종이책 : 2023년 03월 15일 출간

작품소개

책소개

Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena Analyzes t

목차

Section A: Introduction and Overview 1. Backgrounder—Part 1 2. Backgrounder—Part 2 Section B: Preprofessional Education 3. Introduction: Preprofessional education 4. Two-year certification and degree programs 5. Four-year undergraduate degree programs 6. The big decision Section C: Graduate and Professional Education 7. Graduate and postgraduate education at a crossroads 8. Master’s degree programs 9. Doctoral and professional programs 10. The big leap Section D: Research and Discovery 11. Drug discovery: Standing on the shoulders of giants 12. Drug discovery processes: When and where the rubber meets the road 13. Drug discovery: Chaos can be your friend or your enemy 14. Research and discovery: Essential partners but just a start Section E: Chemical, Biological, and Healthcare Product Development, Quality Requirements, and Regulatory Affairs 15. Turning a potent agent—a chemical "drug"—into a registered product 16. Chemical development: Synthetic studies and engineering including aspects of batch production and continuous processing 17. Chemical development: Analytical studies 18. FDA path and process: Sponsor’s regulatory tasks for drug approval 19. Development of biological and other healthcare products Section F: Pharmaceutical Research and Development: Concluding Remarks 20. Epilogue

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작가정보

저자(글) Susan Miller

저자(글) Walter Moos

저자(글) Barbara Munk

저자(글) Stephen Munk

저자(글) Charles Hart