Substance Use and Addiction Research

Alan David Kaye , Richard D. Urman , Elyse M. Cornett , Amber Edinoff 지음

Elsevier 2023년 03월 22일 출간 종이책 : 2023년 02월 17일 출간

작품소개

책소개

Substance Abuse and Addiction Research: Methodology, Mechanisms, and Therapeutics is an up-to-date, comprehensive, practical book on research methodologies for substance abuse and addiction that is intended for researchers and consumers of research information at all levels. The book is divided into four major sections, including an Introduction, Research Methodology for clinical trials, animal research and retrospective studies, Mechanisms of Abuse and Addiction, and Investigative Therapeutics: Designing and Measuring Outcomes. It serves a source for addressing all aspects of research design, methods and analysis within the context of the field of opioids, alcohol and other substances. The book covers what is known in the field of quantitative and qualitative research methods, provides future directions, and introduces new models for investigation. It is organized around a translational science framework, with the contents addressing substance use/addiction research in the context of epidemiology, etiology, intervention efficacy and effectiveness, and implementation of evidence-informed interventions. Presents a practical, easy to read text designed to appeal to both experienced and beginner researchers in the field of substance abuse/addiction science Provides a concise, well-organized handbook that is a complete guide to methodologies in conducting substance abuse/addiction research Contains contributions from leading academic institutions Includes ample diagrams, tables and figures to help organize the information for easy reference, along with a list and explanation of existing useful measurement tools, websites, statistical methods and other resources

목차

Basics of Research Methodology 1. Reliability and validity in substance abuse and addiction research2. Animal models3. Translational research strategies4. Experimental design in clinical trials Part 15. Experimental design in clinical trials Part 26. Qualitative and quantitative methods7. Ethical issues in opioids, alcohol, other drugs and addiction-related research: 8. Informatics9. Artificial intelligence and machine learning10. Epidemiology and health services research methods11. Imaging 12. Systematic review and meta-analysisMechanisms of abuse and addiction 13. Abuse and addiction14. Assessment of addiction/pain and neurobiology15. Physiological considerations in opioid addiction16. Basic pharmacology - opioid substances17. Basic pharmacology - non-opioid substances18. Types of addiction19. Substance use 20. Special study populationsInvestigative Therapeutics: Designing studies and measuring outcomes21. General therapy strategies in substance addiction22. Alternative Therapy Strategies in Addiction23. Drug testing and adherence monitoring24. Pharmacogenetics - Genes, genetics, genomics and epigenetics25. Novel therapeutic strategies effectiveness26. Methods of psychosocial interventions27. Principles of vaccine development28. Drug policy analysis29. Implementation science: Theories, models and frameworks30. Designing and testing population-based prevention programs31. New vistas in research

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작가정보

저자(글) Alan David Kaye

저자(글) Richard D. Urman

저자(글) Elyse M. Cornett

저자(글) Amber Edinoff