Nanomaterials in Advanced Medicine

Hossein Hosseinkhani 지음

Wiley-VCH 2019년 02월 21일 출간

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A comprehensive and multidisciplinary review of the fundamental concepts and medical applications of nanomaterials development technology Nanomedicine offers a range of multi-interdisciplinary approaches and brings together the field of chemistry, pharmaceutical science, biology, and clinical medicines by focusing on design and preparation of biodegradable or non-biodegradable biomaterials for their biological, medical, and pharmaceutical applications. Nanomaterials in Advanced Medicine reviews the concepts and applications of the combination of the technology of biology and engineering that are emerging as an integral aspect of today?s advanced medicine. Nanomedicine provides the technology for imaging, cancer treatment, medical tools, bone treatment, drug delivery, diagnostic tests, drug development, angiogenesis and aims to exploit the improved and often novel physical, chemical, and biological properties of materials at the nanometer scale. Designed to provide a broad survey of the field, Nanomaterials in Advanced Medicine is divided into three main sections: Nanophysics, Nanochemistry, and Nanomedicine. Each chapter describes in detail the most current and valuable methods available and contains numerous references to the primary literature. This important book: -Offers a field guide for biologists and physicians who want to explore the fascinating world of nanotechnology -Contains a comprehensive review of the topic from a noted expert in the field -Includes an introduction to nanotechnology and explores the synthesis, structure and properties of various types of nanobiomaterials -Bridges the gap between various aspects of nanomaterials? development technology and their applications Written for pharmaceutical chemists, biotechnologists, life scientists, materials scientists, polymer chemists, and biochemists, Nanomaterials in Advanced Medicine provides a must-have guide to the fundamental concepts and curr

목차

Preface ix 1 Introduction to Nanotechnology 1 1.1 Introduction 1 1.2 Importance of Size in Nanotechnology 2 1.3 Approaches in Nanotechnology 2 1.3.1 Top-Down Approach 2 1.3.2 Bottom-Up Approach 3 1.4 Impact of Nanotechnology 4 1.4.1 Sensors for the Automotive Industry 4 1.4.2 Health and Medicine 5 1.4.3 Energy and Environment 5 1.4.4 National Security 5 1.5 Nanotechnology Applications 6 1.5.1 Information Technology 6 1.5.2 Energy 6 1.5.3 Medicine 6 1.5.4 Consumer Goods 6 1.6 Summary and Challenges 6 References 8 2 Biomaterials in Medicine 11 2.1 Introduction 11 2.2 Biodegradable Polymers 20 2.3 Natural Biomaterials 25 2.3.1 Gelatin 26 2.3.2 Pectin 27 2.3.3 Chitosan 28 2.3.4 Cyclodextrins (CDs) 29 2.3.5 Dextran, Dextran Spermine (D-SPM) 30 2.3.6 Miscellaneous Polysaccharide Polymers 32 2.3.6.1 Pullulan 32 2.3.6.2 Schizophyllan 33 2.3.6.3 Alginic Acid 33 2.3.6.4 Hydroxypropyl Cellulose 33 2.3.6.5 Glycosaminoglycans 33 2.3.7 Modified Polysaccharides as Gene Delivering Agents 35 2.3.8 Cationic Lipid 38 2.4 Biodegradable Nanoparticles 39 References 40 3 Classification of Nanomaterials 47 3.1 Introduction 47 3.2 Classification of Nanomaterials 48 3.2.1 Nanoparticles 48 3.2.2 Nanofibers, Nanowires, and Nanorods 49 3.2.3 Self-assembly of Proteins and Peptides 52 3.3 Nanocarriers 54 3.3.1 Nanocarriers in Gene Therapy Technology 54 3.3.2 Nanocarriers in siRNA Technology 55 3.3.3 Colloidal Carrier System 57 3.3.4 Nanoparticulate System 59 3.4 Nanoscaffolding Materials 59 References 60 4 Nanomaterials in Gene Therapy Technology 63 4.1 Introduction 63 4.2 Approaches to Gene Therapy 64

작가정보

저자(글) Hossein Hosseinkhani

Hossein Hosseinkhani received his Ph.D. degree in Polymer Chemistry from Kyoto University, Japan. Thereafter, he was offered the prestigious JSPS Fellowship of Japan at the Institute for Frontier Medical Sciences, Kyoto University Hospital to extend his research and to develop stem cells technology based on drug delivery systems for tissue engineering applications. Dr. Hosseinkhani was selected as ICYS Research Fellow of Japan because of his creative research in biomaterials science fields (International Center for Young Scientists (ICYS), Notational Institute for Materials Science). He was a Senior Research Fellow at the International Research Institute for Integrated Medical Sciences, Tokyo Women's Medical University, Japan, and a Visiting Scientist at the Center for Biomedical Engineering, Massachusetts Institute of Technology, USA. Dr. Hosseinkhani has broad experience in life sciences and is expert in nanotechnology, biomaterials, drug delivery, 3D in vitro systems, bioreactor technology, and bioengineering stem cells technology. He has long experience in both academia and industry in biomedical engineering research and development, which includes several years of basic science research experience in a number of premier institutions related to the structure and function of biomaterials, and in polymer-based and mineral-based medical implants development in the medical device industry.