Introduction to Modern Virology

Nigel J. Dimmock , Andrew J. Easton , Keith N. Leppard 지음

Wiley-Blackwell 2015년 12월 28일 출간

작품소개

책소개

Praised forits clarity of presentation and accessibility, Introduction to Modern Virology has been a successful student text for over 30 years. It provides a broad introduction to virology, which includes the nature of viruses, the interaction of viruses with their hosts and the consequences of those interactions that lead to the diseases we see. This new edition contains a number of important changes and innovations including: The consideration of immunology now covers two chapters, one on innate immunity and the other on adaptive immunity, reflecting the explosion in knowledge of viral interactions with these systems. The coverage of vaccines and antivirals has been expanded and separated into two new chapters to reflect the importance of these approaches to prevention and treatment. Virus infections in humans are considered in more detail with new chapters on viral hepatitis, influenza, vector-borne diseases, and exotic and emerging viral infections, complementing an updated chapter on HIV. The final section includes three new chapters on the broader aspects of the influence of viruses on our lives, focussing on the economic impact of virus infections, the ways we can use viruses in clinical and other spheres, and the impact that viruses have on the planet and almost every aspect of our lives. A good basic understanding of viruses is important for generalists and specialists alike. The aim of this book is to make such understanding as accessible as possible, allowing students across the biosciences spectrum to improve their knowledge of these fascinating entities.

목차

Preface 00 About the Companion Website 00 PART I THE NATURE OF VIRUSES 00 Chapter 1 Towards a Definition of a Virus 00 1.1 Discovery of Viruses 00 1.2 Multiplication of Viruses 00 1.3 The Virus Multiplication Cycle 00 1.4 Viruses can be Defined in Chemical Terms 00 1.5 Multiplication of Bacterial and Animal Viruses is Fundamentally Similar 00 1.6 Viruses can be Manipulated Genetically 00 1.7 Properties of Viruses 00 1.8 Origin of Viruses 00 Key Points 00 Further Reading 00 Chapter 2 The Stucture of Virus Particles 00 2.1 Virus Particles are Constructed from Subunits 00 2.2 The Structure of Filamentous Viruses and Nucleoproteins 00 2.3 The Structure of Isometric Virus Particles 00 2.4 Enveloped (Membrane-Bound) Virus Particles 00 2.5 Virus Particles with Head-Tail Morphology 00 2.6 Frequency of Occurrence of Different Virus Particle Morphologies 00 2.7 Principles of Disassembly: Virus Particles are Metastable 00 Key Points 00 Further Reading 00 Chapter 3 Outline 00 3.1 Classification on the Basis of Disease 00 3.2 Classification on The Basis of Host Organism 00 3.3 Classification on The Basis of Virus Particle Morphology 00 3.4 Classification on The Basis of Viral Nucleic Acids 00 3.5 Classification on The Basis of Taxonomy 00 3.6 Satellites, Viroids and Prions 00 Key Points 00 Questions 00 Further Reading 00 Chapter 4 The Evolution of Viruses 00 4.1 Mechanisms of Virus Evolution 00 4.2 The Potential for Rapid Evolution: Mutation and Quasispecies 00 4.3 Rapid Evolution: Recombination 00 4.4 Rapid Evolution: Reassortment 00 4.5 Evolution to Find a Host, and Subsequent Co-Evolution with the Host 00 Key Points 00

작가정보

저자(글) Nigel J. Dimmock

저자(글) Andrew J. Easton

저자(글) Keith N. Leppard