Pocket Guide to GastrointestinaI Drugs

M. Michael Wolfe 지음

Wiley-Blackwell 2014년 01월 02일 출간

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책소개

Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide.Brought to you by many of the world's leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use.Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders.Key features include:Introduction of drug classBasic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerationsDosing information for each GI condition and on- and off-label useConsistent use of both generic and trade names throughoutSpecific reference to drug use in pediatric patients and during pregnancyPerfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists.

목차

List of contributors, xiPreface, xviPART I: UPPER GI TRACT1 Prokinetic agents and antiemetics, 3Hemangi Kale and Ronnie FassProkinetics, 3Antiemetic agents, 7Recommended reading, 142 Proton pump inhibitors, 15Wanda P. Blanton and M. Michael WolfeIntroduction, 15Mechanism of action, pharmacodynamics, kinetics, 15Clinical use and dosing, 18Adverse effects/safety, 27Recommended reading, 283 Histamine H2-receptor antagonists, 31Kentaro SuganoIntroduction, 31Mechanism of action, 31Pharmacology, 33Clinical effectiveness, 40Adverse events, 41Recommended reading, 424 Prostaglandins and other mucosal protecting agents, 44Carlos Sostres and Angel LanasIntroduction of drug class, 44Physicochemical properties, 45Formulations and recommended dosages, 46Mechanism of action, 47Drug interactions, 48Pharmacokinetics, 49Clinical effectiveness, 49Toxicity, 51Pregnancy classes, 52Other mucosal protecting agents, 52Recommended reading, 54PART II: SMALL AND LARGE INTESTINE5 5-HT modulators and other antidiarrheal agents and cathartics, 59Albena Halpert and Douglas DrossmanIntroduction, 595-HT modulators used in the management of GI disorders, 595-HT agents approved in the US for specific GI indications, 60Medications used for the treatment of chronic constipation, 71Medications used for the treatment of narcotic-induced constipation, 76Antidiarrheal agents, 76Conclusion, 80Recommended reading, 806 5-aminosalicylates, 82Hannah L. Miller and Francis A. FarrayeIntroduction, 82Preparations, 82Clinical use and efficacy, 84P

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저자(글) M. Michael Wolfe

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Michael Wolfe, M.D is a former Chair of the FDA's advisory board for gastrointestinal drugs. He has achieved significant recognition for his interest in acid-related disorders, specifically GERD, NSAID-associated gastroduodenal ulcers, gastrinoma and other neuroendocrine tumors. He is on the editorial boards of Digestive Diseases and Sciences and Regulatory Peptides, and served as a member of the editorial board of The American Journal of Physiology. He hasedited several textbooks, including Therapy of Digestive Disorders and Heartburn: Extinguishing the Fire Inside. In total, he's authored over 300 articles, chapters, abstracts and reviews.Robert C. Lowe, M.D. is the author of numerous book chapters and articles, and is co-editor of Educational Review Manual in Gastroenterology and GI Emergencies: A Quick Reference Guide. For the past 4 years, he has served as the chairman of the Medical Advisory Committee of the American Liver Foundation, New England Chapter and he is currently serving as a member of the Education and Training Committee of the American Gastroenterological Association.