Mitochondria

Immo E. Scheffler 지음

Wiley-Liss 2011년 09월 20일 출간

작품소개

책소개

quot;This volume inspires. It certainly will be much appreciated by cell biologists all over the world.quot;Quarterly Review of Biology, March 2009This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles known as mitochondria.This new edition brings readers completely up to date on the many significant findings that have occurred in the eight years since the book was first published. As in that seminal first edition, the second edition tackles the biochemistry, genetics, and pathology of mitochondria in different organisms. The new edition provides thorough updates of all literature concerning this vital organelle, its functions, ongoing research surrounding it, and its importance vis-#224;-vis a broad range of issues in cellular and molecular biology. The book includes detailed descriptions of current and developing technologies around mitochondrial research and discovery, and highlights subjects that are growing, such as the use of proteomics.This book is an invaluable resource for all geneticists, biologists, and educators in life sciences. It is also of interest for advanced students in genetics and molecular biology.

목차

I. HISTORY.References.II. EVOLUTIONARY ORIGIN OF MITOCHONDRIA.References.III. STRUCTURE AND MORPHOLOGY. INTEGRATION INTO THE CELL.3.1 Structure and Morphology.3.2 Integration into the Cell.3.2.1 Distribution in the Cytosol.3.2.2 Interaction with Cytoskeleton.3.3. The dynamics of mitochondrial morpholoy.3.3.1 Mitochondrial Shape Changes.3.3.1.1 Fission.3.3.1.2 Fusion.3.3.2. Distribution during Cell Division.3.3.3. During Cell Differentiation.3.3.4. Turnover and Degradation.3.3.5. Mitochondrial Alterations in Apoptosis.3.3.6. Unsolved Problems for the Future.References.IV. BIOGENESIS OF MITOCHONDRIA.4.1 The Mitochondrial Genome.4.1.1. Introduction.4.1.2. The Mitochondrial Genome in Metazoans.4.1.3. The Mitochondrial Genome in Plants.4.1.4. The Mitochondrial Genome in Fungi.4.1.5. The Mitochondrial Genome in Kinetoplastid Protozoa.4.1.6. Mitochondrial Plasmids.4.1.6.1. Fungal senescence.4.1.6.2. Phytopathogenicity.4.1.6.3. Cytoplasmic male sterility (CMS).4.2 Nuclear Genes encoding Mitochondrial Proteins.4.2.1. Enzymes Required for Maintenance and Expression of the Mitochondrial.Genome.4.2.2. Nucleo-mitochondrial Interactions.4.2.2.1 Introduction..4.2.2.2. In Yeast, Saccharomyces cerevisiae.4.2.2.3 Regulation of nuclear respiratory genes in mammalian cells.4.2.2.4. Co-evolution of nuclear and mitochondrial genomes.4.3 Replication and Maintenance of Mitochondrial DNA.4.3.1. DNA Replication in Mammalian Mitochondria.4.3.2. mtDNA Repair in Mammalian Mitochondria.4.3.3. Recombination in Mammalian Mitochondria.4.3.4. mtDNA Maintenance and Replication in other Organisms.4.4 Transcription of Mitochondrial DNA - RNA Metabolism.4.4.1. Transcription in Mammalian Mitochondria.4.4.2. Transcription of mtDNA in the Yeast Saccharomyces cerevisiae.4.4.3. Transcription of mtDNA in Plant Mitochondria.4.4.4. Transcription

출판사 서평

"This volume inspires. It certainly will be much appreciated by cell biologists all over the world." (Quarterly Review of Biology, March 2009)"Scheffler of California San Diego uses crisp, clear writing style and employs a broad perspective of current research and understanding of mitochondria." (CHOICE, April 2008)

인물정보

저자(글) Immo E. Scheffler

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Immo E. Scheffler, PhD, is Professor in the Division of Biology (Molecular Biology Section) at the University of California, San Diego. In addition to this well-received book, Dr. Scheffler has more than 100 original publications in scientific literature and has written numerous book chapters.