Antimicrobial Resistance in the Environment

Patricia L. Keen 지음

Wiley-Blackwell 2011년 11월 30일 출간

작품소개

책소개

Examines effects of the environmental distribution of antimicrobial resistance genes on human health and the ecosystemResistance genes are everywhere in naturem-in pathogens, commensals, and environmental microorganisms. This contributed work shows how the environment plays a pivotal role in the development of antimicrobial resistance traits in bacteria and the distribution of resistant microbial species, resistant genetic material, and antibiotic compounds. Readers will discover the impact of the distribution in the environment of antimicrobial resistance genes and antibiotics on both the ecosystem and human and animal health.Antimicrobial Resistance in the Environment is divided into four parts:Part I, Sources, including ecological and clinical consequences of antibiotic resistance by environmental microbesPart II, Fate, including strategies to assess and minimize the biological risk of antibiotic resistance in the environmentPart III, Antimicrobial Substances and Resistance, including antibiotics in the aquatic environmentPart IV, Effects and Risks, including the effect of antimicrobials used for non-human purposes on human healthRecognizing the intricate links among overlapping complex systems, this book examines antimicrobial resistance using a comprehensive ecosystem approach. Moreover, the book's multidisciplinary framework applies principles of microbiology, environmental toxicology, and chemistry to assess the human and ecological risks associated with exposure to antibiotics or antibiotic resistance genes that are environmental contaminants.Each chapter has been written by one or more leading researchers in such fields as microbiology, environmental science, ecology, and toxicology. Comprehensive reference lists at the end of all chapters serve as a gateway to the primary research in the field.Presenting and analyzing the latest findings in a

목차

PREFACE xiCONTRIBUTORS xvPART I SOURCES 1Chapter 1 Introduction 3Stuart B. LevyChapter 2 Path to Resistance 7Vivian Miao, Dorothy Davies, and Julian DaviesChapter 3 Antibiotic Resistome: A Framework Linking the Clinic and the Environment 15Gerard D. WrightChapter 4 Ecological and Clinical Consequences of Antibiotic Subsistence by Environmental Microbes 29Gautam Dantas and Morten O. A. SommerChapter 5 Importance of Adaptive and Stepwise Changes in the Rise and Spread of Antimicrobial Resistance 43Lucia Fernandez, Elena B. M. Breidenstein, and Robert E. W. HancockChapter 6 Environmental Reservoirs of Resistance Genes in Antibiotic-Producing Bacteria and Their Possible Impact on the Evolution of Antibiotic Resistance 73Paris Laskaris, William H. Gaze and Elizabeth M. H. WellingtonChapter 7 Mechanisms of Bacterial Antibiotic Resistance and Lessons Learned from Environmental Tetracycline-Resistant Bacteria 93Marilyn C. RobertsChapter 8 Environmental Antibiotic Resistome: New Insights from Culture-Independent Approaches 123Isabel S. Henriques, Artur Alves, Maria Jose´ Saavedra, Mark H. M. M. Montforts, and Anto´nio CorreiaPART II FATE 149Chapter 9 Environmental Pollution by Antibiotic Resistance Genes 151Jose Luis Martinez and Jorge OlivaresChapter 10 Quantifying Anthropogenic Impacts on Environmental Reservoirs of Antibiotic Resistance 173Amy Pruden and Mazdak ArabiChapter 11 Antibiotic Resistance in Swine-Manure-Impacted Environments 203Joanne Chee-Sanford, Scott Maxwell, Kristy Tsau, Kelly Merrick, and Rustam AminovChapter 12 Antimicrobial-Resistant Indicator Bacteria in Manure and the Tracking of Indicator Resistance Genes 225Christina S. Ho¨lzel and Karin SchwaigerChapter 13 Municipal Wastewater as a Reservoir of Antibiotic Resistance 241Timothy Lapara an

출판사 서평

“This is an excellent publication, including primary data and detailed explanations of specific studies and techniques as well as review chapters. As both an introduction to a research area and a call for greater study and thought into how we regulate antimicrobial use in all spheres of society to limit further resistance, I highly recommend Antimicrobial resistance in the environment.”& (Phenotype, 1 February 2013)&“This book will be an ideal read for anyone seeking a comprehensive introduction to the many reservoirs and routes a resistance gene may pass through before or after its appearance in a clinical setting. Even experts in the field stand to gain knowledge regarding the complex web that is the issue of antibiotic resistance in the environment.”& (The Quarterly Review of Biology, 1 December 2012)&

작가정보

저자(글) Patricia L. Keen