Nutraceuticals: Efficacy, Safety and Toxicity

Ramesh C. Gupta , Rajiv Lall , Ajay Srivastava 지음

elsevier 2021년 02월 10일 출간

작품소개

책소개

Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines.Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseasesGrants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effectsProvides effective tools to evaluate the potential toxicity of any nutraceuticalIncludes details of regulatory issues as written by international experts

목차

Section I. Applications of nutraceuticals in common diseases and disorders 1. Nutraceuticals in central nervous system diseases: potential mechanisms of neuroprotection 2. Prevention of neurodegenerative disorders by nutraceuticals 3. Cognitive effects of nutraceuticals 4. Nutraceuticals in anxiety and stress 5. Countering cardiovascular diseases with nutraceuticals 6. Nutraceuticals for diabetes and glucose balance 7. Role of nutraceuticals in respiratory and allied diseases 8. Nutraceuticals in hepatic diseases 9. Nutraceuticals in renal diseases 10. Nutraceuticals in gastrointestinal disorders 11. Nutraceuticals in reproductive and developmental disorders 12. Nutraceuticals in ophthalmic diseases 13. Nutraceuticals in dermal diseases 14. Nutraceuticals in arthritis 15. Nutraceuticals in sports activities and fatigue 16. Role of nutraceuticals as adaptogens 17. Nutraceuticals for weight loss 18. Nutraceuticals in cancer prevention 19. Application of ??nano? nutraceuticals in medicine Section II. Models and mechanisms in evaluation of nutraceuticals 20. The biology of nutrients: genetic and molecular principles 21. Genomic and proteomic mechanisms and models in toxicity and safety evaluation of nutraceuticals 22. Transcriptomic profiling for safety and toxicity evaluation of nutraceuticals 23. Target identification and polypharmacology of nutraceuticals 24. Systems pharmacology investigation of mechanism of action of nutraceuticals 25. Noninvasive in vivo optical imaging models for safety and toxicity testing 26. Flow cytometry and light-scattering techniques in evaluation of nutraceuticals 27. Zebrafish as a model system to evaluate the safety and toxicity of nutraceuticals 28. Caenorhabditis elegans: an elegant model organism for evaluating the neuroprotective and neurotherapeutic potential of nutraceuticals 29. Alternative in vitro models for safety and toxicity evaluation of nutraceuticals 30. Mitochondria as a targe

작가정보

저자(글) Ramesh C. Gupta

저자(글) Rajiv Lall

저자(글) Ajay Srivastava